High-resolution computed tomography--physiologic correlation.
High-resolution computed tomography--physiologic correlation.
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高分辨率计算机断层扫描——生理相关性。
DOI：
10.1097/00005382-199323000-00002
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发表时间：
1993
影响因子：
3.3
通讯作者：
Mitzner,W
中科院分区：
文献类型：
--
作者：
Zerhouni,EA;Herold,CJ;Brown,RH;Wetzel,RC;Hirshman,CA;Robotham,JL;Mitzner,W
高分辨率计算机断层扫描（HRCT）作为一种工具，用于调查支气管血管和肺对各种生理和药理刺激的反应是一个新的应用领域。这种方法的潜力最近才在动物实验中进行了研究。迄今为止，研究集中在确定激动剂激发背景下的气道反应，如雾化或静脉注射组胺、等渗盐水、氟烷麻醉和缺氧。同样，生理性HRCT已用于阐明肺循环对急性高血容量和缺氧的反应。早期的结果表明，显着的观察结果可以从HRCT，因为它是唯一现有的方法，不仅检测生理反应，但不同于现有的方法，可以表征他们的网站和局部差异。在这篇文章中，生理HRCT的基本原理和现状。
High-resolution computed tomography (HRCT) as a tool for investigation of bronchovascular and pulmonary responses to various physiologic and pharmacologic stimuli is a new field of application. The potential of this method has only recently been investigated in animal experiments. To date, research has focused on the determination of airway responses in the context of agonist challenge such as aerosolized or iv histamine, isotonic saline, halothane anesthesia, and hypoxia. Likewise, physiologic HRCT has been used in the elucidation of the pulmonary circulatory response to acute hyper-volemia and hypoxia. Early results indicate that significant observations can be derived from HRCT as it is the only existing method that not only detects physiologic responses but, unlike existing methods, can characterize their site and locoregional differences. In this article, the rationale for and present status of physiologic HRCT is presented.