VITAMIN-B6 DEFICIENCY IN THE RHESUS MONKEY - WITH PARTICULAR REFERENCE TO THE OCCURRENCE OF ATHEROSCLEROSIS, DENTAL CARIES, AND HEPATIC CIRRHOSIS
VITAMIN-B6 DEFICIENCY IN THE RHESUS MONKEY - WITH PARTICULAR REFERENCE TO THE OCCURRENCE OF ATHEROSCLEROSIS, DENTAL CARIES, AND HEPATIC CIRRHOSIS
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DOI：
10.1093/ajcn/4.4.318
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发表时间：
1956-01-01
影响因子：
7.1
通讯作者：
GREENBERG, LD
中科院分区：
文献类型：
--
作者：
RINEHART, JF;GREENBERG, LD
本文总结了 6 年对猴子维生素 B6 缺乏症的研究结果。他们发现，血管病变发生在完全缺乏维生素B6 5至6个月后，其特征和分布与人类动脉硬化的自发病变相似。在对部分缺乏维生素B6的猴子进行的长期实验中，出现了肝硬化和肝脏脂肪沉积的变化，并且在2年或更长时间后，龋齿的发生率很高。参考长期部分缺乏维生素Bg可能与人类动脉硬化、肝硬化和龋齿的病因有关的可能性，讨论了猴子的变化的病理学。 A.M.科平。
The results of 6 years' study of vitamin B6deficiency in monkeys are here summarised. They showed that vascular lesions occurred after from 5 to 6 months' complete deprivation of vitamin B6and were similar in character and distribution to spontaneous lesions of arteriosclerosis in man. In long-term experiments with monkeys partly deprived of vitamin B6, cirrhosis and changes in fat deposition in the liver occurred, and after 2 years or more the incidence of dental caries was high.The pathology of the changes in monkeys is discussed with reference to the possibility that long-term partial deficiency of vitamin Bgmay be concerned' in the aetiology of arteriosclerosis, cirrhosis of the liver and dental caries in man. A. M. Copping.