The moderator effects of affective temperaments, childhood abuse and adult stressful life events on depressive symptoms in the nonclinical general adult population
The moderator effects of affective temperaments, childhood abuse and adult stressful life events on depressive symptoms in the nonclinical general adult population
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DOI：
10.1016/j.jad.2015.08.011
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发表时间：
2015-11-15
影响因子：
6.6
通讯作者：
Kusumi, Ichiro
中科院分区：
文献类型：
--
作者：
Nakai, Yukiei;Inoue, Takeshi;Kusumi, Ichiro
背景资料：最近，我们在结构方程模型中证明，根据孟菲斯、比萨、巴黎和圣地亚哥自我问卷版本（TEMPS-A）的气质评估，五种情感气质中有四种是非临床一般成人人群中儿童期虐待和抑郁症状之间的强中介。在这项研究中，我们假设，情感气质，童年虐待，和成年生活事件有调节作用，相互作用的抑郁症状。分层多元回归分析被用来分析这种相互作用model.Methods：286名参与者从非临床一般成人人群进行了研究，使用以下自填式问卷调查：病人健康问卷-9（PHQ-9），生活经历调查（LES），TEMPS-A，和儿童虐待和创伤量表（CATS）。结果：抑郁性气质增强和情绪激动性气质抑制了儿童期虐待的抑郁效应，而易怒性气质增强和情绪激动性气质抑制了成年期负性（压力）生活事件的抑郁效应。成年人积极的生活事件有抑制性调节作用的抑郁症状，增加了循环情感和焦虑的气质。抑郁症symptoms.Limitations的负面生活事件的影响增强，惩罚，和总的童年虐待：由于本研究的主题是非临床的，研究结果不应该推广到情绪障碍患者。在这个横断面研究中，可能有相互依存关系之间的测量variables.Conclusions：本研究中，使用分层多元回归分析与互动，表现出积极和消极的相互作用之间的任何两个情感气质，儿童虐待，和成人生活事件，和抑郁症状的影响，在非临床一般成人人群。情感气质，童年虐待和成年生活事件对抑郁症状的重要调节作用。(C)© 2015 Elsevier B. V.版权所有
Background: We recently demonstrated in the structural equation modeling that four of five affective temperaments, as measured by the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego auto-questionnaire version (TEMPS-A), are strong mediators between childhood abuse and depressive symptoms in the nonclinical general adult population. In this study, we hypothesized that affective temperaments, childhood abuse, and adult life events have moderator effects that interact with one another on depressive symptoms. The hierarchical multiple regression analysis was used to analyze this interaction model.Methods: The 286 participants from the nonclinical general adult population were studied using the following self-administered questionnaire surveys: the Patient Health Questionnaire-9 (PHQ-9), Life Experiences Survey (LES), TEMPS-A, and Child Abuse and Trauma Scale (CATS). The data were analyzed using hierarchical multiple regressions with interactions.Results: Depressive temperament enhanced and hyperthymic temperament inhibited the depressogenic effects of childhood abuse, while irritable temperament enhanced and hyperthymic temperament inhibited the depressogenic effects of adult negative (stressful) life events. Adult positive life events had an inhibitory moderator effect on depressive symptoms that was increased by cyclothymic and anxious temperaments. Neglect, punishment, and total childhood abuse enhanced the effects of negative life events on depressive symptoms.Limitations: As the subjects of this study were nonclinical, the findings should not be generalized to patients with mood disorders. In this cross-sectional study, there may be interdependence between the measured variables.Conclusions: This study, using the hierarchical multiple regression analysis with interaction, demonstrated the positive and negative interactions between any two of affective temperaments, childhood abuse, and adult life events, and the influence on depressive symptoms in the nonclinical general adult population. Important moderator roles for affective temperaments, childhood abuse, and adult life events on depressive symptoms were suggested. (C) 2015 Elsevier B.V. All rights reserved,