A 3D puzzle approach to building protein-DNA structures.
A 3D puzzle approach to building protein-DNA structures.
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构建蛋白质-DNA 结构的 3D 拼图方法。
DOI:
10.1080/21541264.2017.1283387
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发表时间:
2017
期刊:
影响因子:
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通讯作者:
Hinton,DeborahM
中科院分区:
文献类型:
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作者:
Hinton,DeborahM
Despite recent advances in structural analysis, it is still challenging to obtain a high-resolution structure for a complex of RNA polymerase, transcriptional factors, and DNA. However, using biochemical constraints, 3D printed models of available structures, and computer modeling, one can build biologically relevant models of such supramolecular complexes.