THE THALAMO-CORTICAL PROJECTION OF THE NUCLEUS SUBMEDIUS IN THE CAT
THE THALAMO-CORTICAL PROJECTION OF THE NUCLEUS SUBMEDIUS IN THE CAT
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DOI：
10.1002/cne.902060105
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发表时间：
1982-01-01
影响因子：
2.5
通讯作者：
PRICE, JL
中科院分区：
文献类型：
--
作者：
CRAIG, AD;WIEGAND, SJ;PRICE, JL
The cortical projection of the nucleus submedius (Sm) was studied in the cat with autoradiographic and horseradish peroxidase (HRP) methods. Sm projects topographically on to layer 3 of a distinct agranular cortical field that occupies the posterolateral gyrus proreus, the adjacent fundus of the rhinal sulcus and the postero-ventral portion of the medial wall of the presylvian sulcus. This cortical field is denoted the ventrolateral orbital cortex (VLO), consonant with previous nomenclature in the rat (Krettek and Price). The more ventral part (VLO.beta.) is cytoarchitectonically distinct from the dorsal part (VLO.alpha.); the former receives input from the anterior part of Sm (Sma), while the latter receives input from the dorsal and ventral parts of Sm (Smd and Smv). A light input to superficial layer 1 of VLO probably also arises from Sm, and there may be an input to layers 5 and 6. The corticothalamic projection from VLO to Sm reciprocates the ipsilateral thalamocortical projection and also has a moderate contralateral component. A dense, subpial layer 1 input to VLO arises from cells of the ventromedial nucleus (VM) subjacent to Sm. Clusters of cells in VM probably provide input to layer 3 of the cortex in the fundus of the presylvian sulcus, and area 6a.beta. in the lateral wall of the presylvian sulcus and the ventral bank of the cruciate sulcus. Results from the HRP experiments indicate that VLOb and the anteroventral (Smv) portion of VLO.alpha. are reciprocally connected with the ventral agranular insular cortex and the cingulate cortex ipsilaterally, while the posterodorsal (Smd) portion of VLO.alpha. is instead connected with specific portions of the somatosensory cortical areas bilaterally. All portions of VLO.alpha. appear to project to the ventrolateral periaqueductal gray. The related portion of VLO.alpha. may serve as a cortical representation for noxious stimuli in nociception.
