Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses
Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses
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DOI：
10.1016/j.micinf.2020.08.004
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发表时间：
2020-11-01
影响因子：
5.8
通讯作者：
Opota, Onya
中科院分区：
文献类型：
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作者：
Jacot, Damien;Greub, Gilbert;Opota, Onya
RT-PCRS检测SARS-CoV-2RNA是控制新冠肺炎大流行的关键。我们根据样本类型、性别、年龄和卫生单位，分析了220323个RT-PCR结果中的SARS-CoV-2病毒载量。病毒载量在不同年龄之间没有任何差异，似乎不能很好地预测疾病的结果。SARS-CoV-2病毒载量显示出与观察到的RSV和B型流感病毒载量相似的高病毒载量。讨论了病毒载量对预测传染性和评估疾病进展的重要性。(C)2020年，由Elsevier Masson SAS代表巴斯德研究所出版。
RT-PCRs to detect SARS-CoV-2 RNA is key to manage the COVID-19 pandemic. We analyzed SARS-CoV-2 viral loads from 220323 RT-PCR results according to samples types, gender, age, and health units. Viral load did not show any difference across age and appears to be a poor predictor of disease outcome. SARS-CoV-2 viral load showed similar high viral loads than the one observed for RSV and influenza B. The importance of viral load to predict contagiousness and to assess disease progression is discussed. (C) 2020 Published by Elsevier Masson SAS on behalf of Institut Pasteur.