Gold nanorod-sensitized cell death: Microscopic observation of single living cells irradiated by pulsed near-infrared laser light in the presence of gold nanorods
Gold nanorod-sensitized cell death: Microscopic observation of single living cells irradiated by pulsed near-infrared laser light in the presence of gold nanorods
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DOI：
10.1246/cl.2006.500
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发表时间：
2006-05-05
影响因子：
1.6
通讯作者：
Yamada, Sunao
中科院分区：
文献类型：
--
作者：
Takahashi, Hironobu;Niidome, Takuro;Yamada, Sunao
在磷脂酰胆碱钝化金纳米棒 (PC-NR) 存在的情况下，脉冲近红外 (near-IR) 激光照射会损伤培养细胞。当用聚焦脉冲近红外激光照射单细胞时，PC-NRs的光反应在PC-NRs周围的非常小的区域内造成损伤，并实现单细胞的选择性细胞死亡。
Pulsed near-infrared (near-IR) laser irradiation damaged cultured cells in the presence of phosphatidylcholine- passivated gold nanorods (PC-NRs). When single cells were irradiated with a focused pulsed near-IR laser, photoreaction of the PC-NRs caused damage within a very small area around the PC-NRs, and achieved selective cell death of single cells.