Antenatal Hypoxia and Low IQ Values
Antenatal Hypoxia and Low IQ Values
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产前缺氧和低智商值
DOI：
10.1097/00132582-198710000-00010
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
E. Peters
中科院分区：
文献类型：
--
作者：
R. Naeye;E. Peters
我们进行了分析，以确定是否胎儿，产时和新生儿缺氧是智商值低的重要原因。我们前瞻性分析了19,117名儿童的妊娠、围产期和随后的发育数据。正如预期的那样，社会遗传和人口因素对智商分数有很大的影响。考虑到这些影响，在分娩、分娩或新生儿期发生的任何事情都不会影响随后的智商值。同样的情况也适用于早期妊娠紊乱，可能会导致急性胎儿缺氧。相比之下，产前疾病和条件，可以产生亚急性或慢性胎儿缺氧与低智商值。这些产前疾病和条件是母亲妊娠贫血，相对妊娠期低血压，高血压，多胞胎，胎儿生长迟缓。无论是否存在神经系统异常，所有这些发现都是相同的，这表明有时相同的因素参与了认知障碍和神经系统异常的发生。
We undertook analyses to determine if fetal, intrapartum, and neonatal hypoxia are important causes of low IQ values. We analyzed prospectively collected pregnancy, perinatal, and subsequent developmental data for 19,117 children. As expected, sociohereditary and demographic factors had a large influence on IQ scores. Taking these latter influences into consideration, nothing that happened during labor, delivery, or the neonatal period affected subsequent IQ values. The same was true for early pregnancy disorders that can produce acute fetal hypoxia. By contrast, antenatal disorders and conditions that can produce subacute or chronic fetal hypoxia correlated with low IQ values. These antenatal disorders and conditions were maternal gestational anemia, relative gestational hypotension, hypertension, multiple births, and fetal growth retardation. All of these findings were the same whether neurologic abnormalities were absent or present, suggesting that the same factors were sometimes involved in the genesis of cognitive impairments and neurologic abnormalities.