HEXOKINASE1 and glucose-6-phosphate fuel plant growth and development.
HEXOKINASE1 and glucose-6-phosphate fuel plant growth and development.
复制标题
DOI：
10.1242/dev.202346
复制
发表时间：
2023-10
期刊：
影响因子：
4.6
通讯作者：
Morgan Vanderwall;Joshua M. Gendron
中科院分区：
文献类型：
--
作者：
Morgan Vanderwall;Joshua M. Gendron
作为光自养生物，植物产生令人难以置信的色素谱，抗草食性化合物，结构材料和能量中间体。这些生物合成途径有助于植物生长、繁殖和缓解压力。己糖激酶1（HXK 1）是一种代谢酶和葡萄糖传感器，催化己糖的磷酸化，这是许多这些途径的关键入门步骤。然而，以前的研究主要集中在HXK 1的葡萄糖传感和信号传导功能上，而这种酶的催化功能的重要性只是最近才与植物发育有关。在这篇简短的聚焦文章中，我们描述了植物HXK 1的发育意义及其在植物代谢途径中的作用，特别是在葡萄糖-6-磷酸生产中。此外，我们描述了新兴的新陈代谢和发展之间的联系，并建议HXK 1信号和催化活性调节植物发育的离散领域。
As photoautotrophic organisms, plants produce an incredible spectrum of pigments, anti-herbivory compounds, structural materials and energic intermediates. These biosynthetic routes help plants grow, reproduce and mitigate stress. HEXOKINASE1 (HXK1), a metabolic enzyme and glucose sensor, catalyzes the phosphorylation of hexoses, a key introductory step for many of these pathways. However, previous studies have largely focused on the glucose sensing and signaling functions of HXK1, and the importance of the enzyme's catalytic function is only recently being connected to plant development. In this brief Spotlight, we describe the developmental significance of plant HXK1 and its role in plant metabolic pathways, specifically in glucose-6-phosphate production. Furthermore, we describe the emerging connections between metabolism and development and suggest that HXK1 signaling and catalytic activity regulate discrete areas of plant development.