Ni-Catalyzed Direct Carboxylation of Benzyl Halides with CO2
Ni-Catalyzed Direct Carboxylation of Benzyl Halides with CO2
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DOI：
10.1021/ja311045f
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发表时间：
2013-01-30
影响因子：
15
通讯作者：
Martin, Ruben
中科院分区：
文献类型：
--
作者：
Leon, Thierry;Correa, Arkaitz;Martin, Ruben
发展了一种新型镍催化的苄基卤与CO2的羧化反应。所述羧化反应在室温下在温和条件（大气压CO，压力）下进行。与其他类似方法的路线不同，我们的方法不需要明确定义和敏感的有机金属试剂，因此是一个用户友好和操作简单的协议组装苯乙酸。
A novel Ni-catalyzed carboxylation of benzyl halides with CO2 has been developed. The described carboxylation reaction proceeds under mild conditions (atmospheric CO, pressure) at room temperature. Unlike other routes for similar means, our method does not require well-defined and sensitive organometallic reagents and thus is a user-friendly and operationally simple protocol for assembling phenylacetic acids.