Screen-printed Organic Electrochemical Transistors for the detection of ascorbic acid in food
Screen-printed Organic Electrochemical Transistors for the detection of ascorbic acid in food
复制标题
DOI：
10.1016/j.orgel.2017.02.037
复制
发表时间：
2017-06
影响因子：
3.2
通讯作者：
L. Contat-Rodrigo;Clara Pérez-Fuster;José Vicente Lidón-Roger;A. Bonfiglio;E. García-Breijo
中科院分区：
文献类型：
--
作者：
L. Contat-Rodrigo;Clara Pérez-Fuster;José Vicente Lidón-Roger;A. Bonfiglio;E. García-Breijo
传统上用于食品中抗坏血酸（AA）检测的方法通常昂贵且复杂，不适合日常测定。在这项工作中，我们报告使用全PEDOT：PSS有机电化学晶体管（OECTs）的快速，简单和低成本的测定食品中的AA。首先在实验室制备的不同浓度的AA溶液中测试这些OECT的性能。还通过比较具有不同沟道和栅极面积比（γ）的两种OECT的响应，在电流调制、灵敏度、背景信号和检测限（LOD）方面，研究了几何形状对用于AA感测的晶体管性能的影响。栅电极小于沟道（大γ）的OECT显示出最佳的AA传感性能：这些器件显示出更小的背景信号、更高的灵敏度、更大的调制和更好的LOD值（80 μM）。由于富含维生素C的食物中的AA含量在mM范围内，因此这些晶体管可以被认为足够灵敏以定量监测食物中的AA。为了证明所提出的传感器在真实的食品样品中的可靠性，这些晶体管的响应另外在商业橙子汁中测量。与OECTs获得的AA的量是在良好的协议，通过HPLC测定，并在文献中报道的值为橙子汁。此外，这些OECTs可以被认为是有前途的候选人的选择性检测AA的存在下，其他干扰抗氧化剂。
Methods traditionally used for ascorbic acid (AA) detection in food are often expensive and complex, making them unsuitable for day-to-day determinations. In this work, we report on the use of all-PEDOT:PSS Organic Electrochemical Transistors (OECTs) for fast, simple and low-cost determination of AA in food. The performance of these OECTs was tested first with in lab-prepared solutions of AA with different concentrations. The effect of the geometry on the transistors performance for AA sensing was also investigated by comparing the response of two OECTs with different channel and gate areas ratio (γ), in terms of current modulation, sensitivity, background signal and limit of detection (LOD). OECTs with smaller gate electrode than the channel (large γ) show the best performance for AA sensing: these devices display smaller background signal, higher sensitivity, larger modulation and better LOD value (80 μM). Since the AA content in food rich in Vitamin C is in the mM range, these transistors can be considered sensitive enough for quantitatively monitoring AA in food. In order to demonstrate the reliability of the proposed sensors in real food samples, the response of these transistors was additionally measured in a commercial orange juice. The amount of AA obtained with the OECTs is in good agreement with that determined by HPLC and with values reported in the literature for orange juices. Furthermore, these OECTs can be considered promising candidates for the selective detection of AA in the presence of other interfering antioxidants.