Performance of Mini-Mental State Examination (MMSE) in long-stay patients with schizophrenia or schizoaffective disorders in a psychiatric institute
Performance of Mini-Mental State Examination (MMSE) in long-stay patients with schizophrenia or schizoaffective disorders in a psychiatric institute
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DOI：
10.1016/j.psychres.2016.04.116
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发表时间：
2016-07-30
影响因子：
11.3
通讯作者：
Chong, Siow Ann
中科院分区：
文献类型：
--
作者：
Ong, Hui Lin;Subramaniam, Mythily;Chong, Siow Ann
研究发现，年龄和教育程度与老年人的认知能力有关。然而，临床因素(如发病年龄、住院时间、抗精神病药物类型和病程)与精神分裂症患者的认知功能之间的关系却知之甚少。本研究旨在探讨社会人口学及临床因素对新加坡精神病院住院精神分裂症或分裂情感性精神障碍患者认知领域的影响。精神卫生研究所(IMH)对被诊断为精神分裂症或分裂情感障碍的患者(n=110)进行了单阶段访谈。对所有参与者进行MMSE测试。收集了有关社会人口学特征、吸烟、饮酒和病史的数据。年龄、性别和教育水平与MMSE得分显著相关。在调整了所有SoDo-人口统计学相关因素后，住院时间较长仍然显著预测较低的MMSE得分。住院时间与认知功能独立相关。应及早进行认知干预，如身体和心理锻炼，以改善预后。(C)2016年提交人。爱思唯尔爱尔兰有限公司出版。爱思唯尔爱尔兰有限公司出版。这是一篇CC BY-NC-ND许可证下的开放获取文章。
Studies have found that age and education were associated with cognition in older adults. However, little is known how clinical factors (e.g. age of illness onset, length of hospital stay, type of anti psychotic medications, and duration of illness) are associated with cognitive functioning in patients with schizophrenia. This study aimed to examine the influence of socio-demographic and clinical factors on cognitive domains measured using Mini-Mental State Examination (MMSE) among patients with schizophrenia or schizoaffective disorders residing in a psychiatric institute in Singapore. A single-phase interview was conducted at the Institute of Mental Health (IMH) in patients diagnosed with schizophrenia or schizoaffective disorders (n=110). MMSE was administered to all participants. Data on socio-demographic characteristics, smoking, alcohol consumption, and medical history were collected. Age, gender, and level of education were significantly associated with MMSE scores. After adjusting for all sodo-demographic correlates, longer length of hospital stay remained significant in predicting lower MMSE scores. Length of hospital stay was independently associated with cognitive functioning. Early interventions for cognition such as physical and mental exercises should be implemented for better prognosis. (C) 2016 The Authors. Published by Elsevier Ireland Ltd. Published by Elsevier Ireland Ltd. This is an open access article under the CC BY-NC-ND license.