Antisocial Personality Disorder, Alcohol, and Aggression
Antisocial Personality Disorder, Alcohol, and Aggression
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发表时间：
2001
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影响因子：
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通讯作者：
F. Moeller;D. Dougherty
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文献类型：
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作者：
F. Moeller;D. Dougherty
流行病学研究和实验室研究一直将饮酒与攻击性联系在一起。然而，并不是所有人都会在酒精的影响下表现出更强的攻击性。最近的研究表明，有反社会人格障碍(ASPD)的人可能比没有ASPD的人更容易受到与酒精有关的攻击。作为一个群体，患有ASPD的人比没有ASPD的人有更高的酒精依赖率和更多的酒精相关问题。同样，在实验室研究中，患有ASPD的人在饮酒后表现出比没有ASPD的人更多的攻击性行为。ASPD与酒精相关攻击之间的联系可能源于生物学因素，例如与ASPD相关的某些大脑化学物质(如5-羟色胺)的功能受损，或较高推理或“执行”脑区的活动。或者，ASPD与酒精相关攻击之间的联系可能源于一些尚不确定的因素(S)，这些因素总体上增加了攻击的风险。
Epidemiologic studies and laboratory research consistently link alcohol use with aggression. Not all people, however, exhibit increased aggression under the influence of alcohol. Recent research suggests that people with antisocial personality disorder (ASPD) may be more prone to alcohol-related aggression than people without ASPD. As a group, people with ASPD have higher rates of alcohol dependence and more alcohol-related problems than people without ASPD. Likewise, in laboratory studies, people with ASPD show greater increases in aggressive behavior after consuming alcohol than people without ASPD. The association between ASPD and alcohol-related aggression may result from biological factors, such as ASPD-related impairments in the functions of certain brain chemicals (e.g., serotonin) or in the activities of higher reasoning, or “executive,” brain regions. Alternatively, the association between ASPD and alcohol-related aggression may stem from some as yet undetermined factor(s) that increase the risk for aggression in general.