Melatonin secretion after surgery
Melatonin secretion after surgery
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DOI：
10.1016/s0140-6736(00)02795-1
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发表时间：
2000-10-07
期刊：
影响因子：
168.9
通讯作者：
Bixler, EO
中科院分区：
文献类型：
--
作者：
Cronin, AJ;Keifer, JC;Bixler, EO
术后睡眠障碍是常见的。我们检查了七名术后患者的褪黑激素浓度是否与这种干扰有关。夜间褪黑激素浓度显着（p=0.005）低于第一次手术后的第二或第三个晚上。这一发现提出了可能性，褪黑激素抑制和相关的睡眠障碍可能会防止褪黑激素替代。
Sleep disturbance is common postoperatively. We examined whether melatonin concentrations were related to this disturbance in seven postoperative patients. Nocturnal concentrations of melatonin were significantly (p=0.005) lower on the first than on the second or third nights after surgery. This finding raises the possibility that melatonin suppression and associated sleep disturbance might be prevented by melatonin replacement.