Mild and selective reduction of imines: Formation of an unsymmetrical macrocycle
Mild and selective reduction of imines: Formation of an unsymmetrical macrocycle
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DOI：
10.1021/jo049197u
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发表时间：
2004-12-10
影响因子：
3.6
通讯作者：
MacLachlan, MJ
中科院分区：
文献类型：
--
作者：
Gallant, AJ;Patrick, BO;MacLachlan, MJ
在对5的研究过程中，得到了一个含6个亚胺的[3 + 3]席夫碱大环，一个部分还原的席夫碱大环，6，具有一个CH_2NH和5个亚胺基团。对照实验和氘标记表明，大环是由反应过程中产生的苯并咪唑啉减少。苯并咪唑啉类化合物可作为亚胺类化合物温和、选择性还原的方便试剂。
During investigations of 5, a [3 + 3] Schiff-base macrocycle with six imines, a partially reduced Schiff-base macrocycle, 6, possessing one CH2NH and five imine groups was obtained. Control experiments and deuterium labeling indicate that the macrocycle is reduced by a benzimidazoline generated during the reaction. Benzimidazolines may be convenient reagents for the mild and selective reduction of imines.