Advances in CRC Prevention: Screening and Surveillance
Advances in CRC Prevention: Screening and Surveillance
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DOI：
10.1053/j.gastro.2018.01.069
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发表时间：
2018-05-01
期刊：
影响因子：
29.4
通讯作者：
Rex, Douglas K.
中科院分区：
文献类型：
--
作者：
Dekker, Evelien;Rex, Douglas K.
结直肠癌(CRC)是世界上最常见的癌症之一，也是癌症导致的死亡原因之一。然而，在无症状的患者中，结直肠癌可以在可治愈的阶段被检测到，几项研究表明，接受筛查的患者的死亡率低于没有筛查的患者。在结直肠癌筛查中使用结肠镜检查还可以检测到癌前病变息肉，这些息肉可以在手术过程中直接切除，从而降低癌症的发生率。在过去的十年中，有令人信服的证据表明，结肠镜检查作为结直肠癌预防工具的有效性与手术质量有关。本综述旨在通过提高结肠镜检查的发现和提高大肠病变切除的完整性和安全性来提供最新的研究进展。
Colorectal cancer (CRC) is among the most commonly diagnosed cancers and causes of death from cancer across the world. CRC can, however, be detected in asymptomatic patients at a curable stage, and several studies have shown lower mortality among patients who undergo screening compared with those who do not. Using colonoscopy in CRC screening also results in the detection of precancerous polyps that can be directly removed during the procedure, thereby reducing the incidence of cancer. In the past decade, convincing evidence has appeared that the effectiveness of colonoscopy as CRC prevention tool is associated with the quality of the procedure. This review aims to provide an up-to-date overview of recent efforts to improve colonoscopy effectiveness by enhancing detection and improving the completeness and safety of resection of colorectal lesions.