Surgical Treatment of Pancreatic Cancer
Surgical Treatment of Pancreatic Cancer
复制标题
DOI：
10.1196/annals.1414.024
复制
发表时间：
2008-01-01
期刊：
影响因子：
--
通讯作者：
Buechler, Markus W.
中科院分区：
文献类型：
--
作者：
Loos, Martin;Kleeff, Joerg;Buechler, Markus W.
胰腺癌是一种侵袭性疾病，总体5年生存率低于5%。迄今为止，手术切除仍是治疗局限性胰腺癌的基础，也是治愈的唯一机会。由于手术技术和围手术期护理的不断改进，胰腺切除术已发展成为安全的外科手术，对于高容量中心的经验丰富的外科医生来说，死亡率低，发病率可接受。最近，更积极的方法，包括扩大淋巴结切除术，血管切除术，手术治疗复发性或复发性疾病，和多模式方案已被建议改善长期结果。本文概述了当前的标准手术，并总结了胰腺癌外科治疗的新策略。
Pancreatic cancer is an aggressive disease with an overall 5-year survival rate of less than 5%. Up to date, surgical resection represents the basis of treatment for localized pancreatic cancer and remains the only chance for cure. Due to continuous improvements in surgical techniques and perioperative care, pancreatic resections have evolved into safe surgical procedures with low mortality and acceptable morbidity rates for experienced surgeons in high-volume centers. Recently, more aggressive approaches including extended lymphadenectomy, vascular resection, surgery for metastastic or recurrent disease, and multimodal regimens have been suggested to improve long-term outcome. This article provides an overview on current standard procedures and summarizes new strategies in the surgical treatment of pancreatic cancer.