Vital Signs: Trends in Incidence of Cancers Associated with Overweight and Obesity - United States, 2005-2014.
Vital Signs: Trends in Incidence of Cancers Associated with Overweight and Obesity - United States, 2005-2014.
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DOI：
10.15585/mmwr.mm6639e1
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发表时间：
2017-10-03
期刊：
影响因子：
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通讯作者：
Richardson LC
中科院分区：
文献类型：
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作者：
Steele CB;Thomas CC;Henley SJ;Massetti GM;Galuska DA;Agurs-Collins T;Puckett M;Richardson LC
超重和肥胖与至少 13 种不同类型癌症的风险增加有关。 2014 年美国癌症统计数据用于评估发病率，2005 年至 2014 年的数据用于评估与超重和肥胖相关的癌症趋势（食道腺癌；乳腺癌[绝经后妇女]、结肠癌和直肠癌、子宫内膜癌、胆囊癌、贲门癌、肾癌、肝癌、卵巢癌、胰腺癌和甲状腺癌；脑膜瘤；和多发性骨髓瘤）按性别、年龄、种族/民族、州、地理区域和癌症部位分类。由于结直肠癌筛查可以通过在癌前息肉癌变之前进行检测来降低结直肠癌的发病率，因此对有和没有结直肠癌的趋势进行了分析。 2014年，美国约有631,000人被诊断出患有与超重和肥胖相关的癌症，占所有诊断癌症的40%。老年人（年龄≥50岁）中与超重和肥胖相关的癌症发病率高于年轻人；女性高于男性；与其他群体相比，非西班牙裔黑人和非西班牙裔白人成年人的这一比例更高。 2005 年至 2014 年期间，超重和肥胖相关癌症的发病率因年龄、癌症部位和州而异。除结直肠癌外，20-74岁人群的发病率显着增加； ≥75岁人群下降； 32 个州有所增加；并在 16 个州和哥伦比亚特区保持稳定。在美国，与超重和肥胖相关的癌症负担很高。除结直肠癌外，与超重和肥胖相关的癌症的发病率在某些年龄组和州有所增加。通过努力预防和控制超重和肥胖，可以减轻超重和肥胖相关癌症的负担。全面的癌症控制策略，包括使用循证干预措施来促进健康体重，可能有助于降低美国这些癌症的发病率。
Overweight and obesity are associated with increased risk of at least 13 different types of cancer. Data from the United States Cancer Statistics for 2014 were used to assess incidence rates, and data from 2005 to 2014 were used to assess trends for cancers associated with overweight and obesity (adenocarcinoma of the esophagus; cancers of the breast [in postmenopausal women], colon and rectum, endometrium, gallbladder, gastric cardia, kidney, liver, ovary, pancreas, and thyroid; meningioma; and multiple myeloma) by sex, age, race/ethnicity, state, geographic region, and cancer site. Because screening for colorectal cancer can reduce colorectal cancer incidence through detection of precancerous polyps before they become cancerous, trends with and without colorectal cancer were analyzed. In 2014, approximately 631,000 persons in the United States received a diagnosis of a cancer associated with overweight and obesity, representing 40% of all cancers diagnosed. Overweight- and obesity-related cancer incidence rates were higher among older persons (ages ≥50 years) than younger persons; higher among females than males; and higher among non-Hispanic black and non-Hispanic white adults compared with other groups. Incidence rates for overweight- and obesity-related cancers during 2005–2014 varied by age, cancer site, and state. Excluding colorectal cancer, incidence rates increased significantly among persons aged 20–74 years; decreased among those aged ≥75 years; increased in 32 states; and were stable in 16 states and the District of Columbia. The burden of overweight- and obesity-related cancer is high in the United States. Incidence rates of overweight- and obesity-related cancers except colorectal cancer have increased in some age groups and states. The burden of overweight- and obesity-related cancers might be reduced through efforts to prevent and control overweight and obesity. Comprehensive cancer control strategies, including use of evidence-based interventions to promote healthy weight, could help decrease the incidence of these cancers in the United States.