Depression after alcohol treatment as a risk factor for relapse among male veterans

Depression after alcohol treatment as a risk factor for relapse among male veterans
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DOI:
10.1016/s0740-5472(00)00107-0
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发表时间:
2000-10-01
影响因子:
3.9
通讯作者:
Booth, BM
Booth, BM
中科院分区:
医学2区
文献类型:
--
作者:
Curran, GM;Flynn, HA;Booth, BM

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我们研究了在酒精障碍住院治疗期间和治疗后3个月内测量的饮酒复发和抑郁性精神障碍之间的关系。数据来自298名完成21天住院治疗的退伍军人。在治疗后3、6、9和12个月进行随访。我们使用多元逻辑回归来评估复发与基线/治疗后3个月抑郁指标(Beck抑郁量表; BDI)之间的相关性,控制重要的协变量。我们的研究结果表明:(a)治疗后3个月时,轻度至中度症状的参与者(BDI = 14-19)在随访期间复发的可能性平均是非抑郁症参与者的2.9倍;(B)治疗后3个月时,重度症状的参与者(BDI = 20+)在随访期间复发的可能性平均是非抑郁症参与者的4.9倍。其他分析显示,那些在基线和治疗后3个月报告持续性抑郁症的患者并没有经历比那些在治疗后3个月报告抑郁症的患者更糟糕的结局。(C)2000 Elsevier Science Inc. All rights reserved.
We examined the association between relapse-to-drinking and depressive symptomatology measured during inpatient treatment for alcohol disorder and 3 months posttreatment. Data were obtained from 298 veterans who completed 21-day inpatient treatment. Follow-up interviews were conducted at 3, 6, 9, and 12 months posttreatment. We used multiple logistic regression to assess the association between relapse and baseline/3-month posttreatment measures of depression (Beck Depression Inventory; BDI), controlling for important covariates. Our results showed that (a) the mild-to-moderately symptomatic participants (BDI = 14-19) at 3 months posttreatment were on average 2.9 times more likely than the nondepressed to have relapsed across follow-ups, and (b) the severely symptomatic participants (BDI = 20+) at 3 months posttreatment were on average 4.9 times more likely to have relapsed across follow-ups. Other analyses revealed that those with persistent depressive symptomatology reported at both baseline and 3 months posttreatment did not experience worse outcomes that those who reported symptomatology at 3 months posttreatment alone. (C) 2000 Elsevier Science Inc. All rights reserved.