Colorectal cancer incidence and mortality disparities in new Mexico.
Colorectal cancer incidence and mortality disparities in new Mexico.
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DOI：
10.1155/2014/239619
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发表时间：
2014
影响因子：
1.8
通讯作者：
Wiggins CL
中科院分区：
文献类型：
--
作者：
Hoffman RM;Espey DK;Rhyne RL;Gonzales M;Rajput A;Mishra SI;Stone SN;Wiggins CL
背景。先前的分析表明，新墨西哥西班牙裔和美洲印第安人（AI）没有经历在非西班牙裔白人（NHW）中观察到的结直肠癌（CRC）发病率和死亡率下降。我们评估了最近的数据，以确定种族/民族差异是否持续存在。方法。我们使用1995年至2009年的新墨西哥州监测流行病学和最终结果数据来计算年龄特异性发病率和年龄调整后的总体发病率和肿瘤分期。我们使用国家卫生统计中心的数据计算死亡率。我们使用连接点回归来确定年龄调整后发病率的年百分比变化（APC）。分析按种族/民族和性别分层。结果。NHW的发病率继续下降（男性APC为- 1.45%，女性APC为- 1.06%），而AI（男性为1.67%，女性为1.26%）和西班牙裔女性（0.24%）的发病率无显著增加。西班牙裔男性的APC在2001年开始上升（3.33%,P = 0.06），然后下降（- 3.10%,P = 0.003）。75岁及以上的非裔美国人和西班牙裔美国人的发病率下降。所有组的晚期癌症发病率保持稳定。美国黑人和西班牙裔的死亡率显著下降。结论。新墨西哥州CRC的种族/民族差异依然存在。发病率差异可能与风险因素或接受筛查的机会有关；死亡率的差异可能是由于筛查或治疗的护理模式。
Background. Previous analyses indicated that New Mexican Hispanics and American Indians (AI) did not experience the declining colorectal cancer (CRC) incidence and mortality rates observed among non-Hispanic whites (NHW). We evaluated more recent data to determine whether racial/ethnic differences persisted. Methods. We used New Mexico Surveillance Epidemiology and End Results data from 1995 to 2009 to calculate age-specific incidence rates and age-adjusted incidence rates overall and by tumor stage. We calculated mortality rates using National Center for Health Statistics' data. We used joinpoint regression to determine annual percentage change (APC) in age-adjusted incidence rates. Analyses were stratified by race/ethnicity and gender. Results. Incidence rates continued declining in NHW (APC −1.45% men, −1.06% women), while nonsignificantly increasing for AI (1.67% men, 1.26% women) and Hispanic women (0.24%). The APC initially increased in Hispanic men through 2001 (3.33%, P = 0.06), before declining (−3.10%, P = 0.003). Incidence rates declined in NHW and Hispanics aged 75 and older. Incidence rates for distant-stage cancer remained stable for all groups. Mortality rates declined significantly in NHW and Hispanics. Conclusions. Racial/ethnic disparities in CRC persist in New Mexico. Incidence differences could be related to risk factors or access to screening; mortality differences could be due to patterns of care for screening or treatment.