Sleepiness, fatigue, tiredness, and lack of energy in obstructive sleep apnea

Sleepiness, fatigue, tiredness, and lack of energy in obstructive sleep apnea
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DOI:
10.1378/chest.118.2.372
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发表时间:
2000-08-01
期刊:
影响因子:
9.6
通讯作者:
Chervin, RD
Chervin, RD
中科院分区:
医学1区
文献类型:
--
作者:
Chervin, RD

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研究目的:嗜睡是阻塞性睡眠呼吸暂停综合征(OSAS)的一个关键症状,可以通过多次睡眠潜伏期试验(MSAS)进行客观评估。我们研究了患者更喜欢描述他们的睡眠的术语-嗜睡、疲劳、疲倦或缺乏能量-以及这些术语与客观结果的关系。设计:观察。设置:大学睡眠实验室,患者:阻塞性睡眠呼吸暂停综合征患者转介诊断性多导睡眠描记术和MPERS,方法:数据来自睡眠研究和问卷调查。受试者包括117名男性和73名女性,平均(+/- SD)年龄为49 +/- 13岁,呼吸暂停和呼吸不足率为32 +/- 28/h睡眠,平均睡眠潜伏期为7 ± 5分钟。受试者更频繁地报告疲劳、疲倦和缺乏能量的问题,而不是嗜睡(57%、61%和62%对47%),当被要求选择一个最重要的症状时,更多的患者选择缺乏能量(约40%)比任何其他问题,包括嗜睡(约22%)。嗜睡和呼吸暂停严重程度的客观测量显示与任何症状几乎没有或没有关联,但女性性别与每一个都有显著关联。对OSAS患者来说,疲劳、疲倦或缺乏能量的抱怨可能与嗜睡一样重要,其中女性似乎比男性更频繁地抱怨所有这些抱怨,OSAS的诊断不应该仅仅基于一个人强调疲劳、疲倦或缺乏能量而不是嗜睡的倾向而被排除。
Study objectives: Sleepiness is a key symptom in obstructive sleep apnea syndrome (OSAS) and can be objectively assessed with a multiple sleep latency test (MSLT), We studied the terms that patients prefer to describe their symptoms-sleepiness, fatigue, tiredness, or lack of energy-and how these terms relate to objective findings.Design: Observational.Setting: University-based sleep laboratory,Patients: Consecutive OSAS patients referred for diagnostic polysomnography and an MSLT,Methods: Data were obtained from sleep studies and questionnaires.Results: Subjects included 117 men and 73 women, with a mean (+/- SD) age of 49 +/- 13 years, an apnea and hypopnea rate of 32 +/- 28/h of sleep, and an MSLT mean sleep latency of 7 +/- 5 min. Subjects more frequently reported problems with fatigue, tiredness, and lack of energy than sleepiness (57%, 61%, and 62% vs 47%), When required to select the one most significant symptom, more patients chose lack of energy (about 40%) than any other problem, including sleepiness (about 22%). Objective measures of sleepiness and apnea severity showed little or no association with any symptom, but female gender showed significant associations with each.Conclusions: Complaints of fatigue, tiredness, or lack of energy may be as important as that of sleepiness to OSAS patients, among whom women appear to have all such complaints more frequently than men, The diagnosis of OSAS should not be excluded based only on a person's tendency to emphasize fatigue, tiredness, or lack of energy more than sleepiness.