A millisecond micromixer via single-bubble-based acoustic streaming
A millisecond micromixer via single-bubble-based acoustic streaming
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DOI：
10.1039/b903687c
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发表时间：
2009-01-01
期刊：
影响因子：
6.1
通讯作者：
Huang, Tony Jun
中科院分区：
文献类型：
--
作者：
Ahmed, Daniel;Mao, Xiaole;Huang, Tony Jun
我们展示了通过基于单气泡的声流在微流控通道内的超高速均匀混合。该装置的工作原理是在微通道内两个层流之间的马蹄形结构中捕获气泡。声波以其共振频率激发捕获的气泡，导致声流，从而扰乱层流并触发两种流体混合。由于该技术设计简单，混合性能优异，混合速度快(几毫秒)，我们的基于单泡的声学微混合器可能被证明对许多生物化学研究和应用有用。
We present ultra-fast homogeneous mixing inside a microfluidic channel via single-bubble- based acoustic streaming. The device operates by trapping an air bubble within a "horse-shoe'' structure located between two laminar flows inside a microchannel. Acoustic waves excite the trapped air bubble at its resonance frequency, resulting in acoustic streaming, which disrupts the laminar flows and triggers the two fluids to mix. Due to this technique's simple design, excellent mixing performance, and fast mixing speed (a few milliseconds), our single-bubble-based acoustic micromixer may prove useful for many biochemical studies and applications.