Verbal learning and memory in agenesis of the corpus callosum.

Verbal learning and memory in agenesis of the corpus callosum.
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DOI:
10.1016/j.neuropsychologia.2014.06.003
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发表时间:
2014-07
期刊:
影响因子:
2.6
通讯作者:
Brown, Warren S.
Brown, Warren S.
中科院分区:
心理学3区
文献类型:
--
作者:
Erickson, Roger L.;Paul, Lynn K.;Brown, Warren S.

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通过评估胼胝体完全或部分发育不全(AgCC)但智力正常的个体,可以阐明半球间相互作用在语言记忆的编码、保留和检索中的作用。本研究使用加州言语学习测试第二版 (CVLT-II) 评估 AgCC 的言语学习和记忆。将 26 名 AgCC 患者与 24 名匹配对照者的 CVLT-II 测量值以及 Donders 的四个 CVLT-II 因素(即注意力广度、学习效率、记忆延迟和记忆不准确)进行比较。患有 AgCC 的个体在延迟记忆因子方面的表现明显低于健康对照组,这可以通过短期和长期延迟自由回忆和提示回忆的显着缺陷得到证实。他们在原始学习中的表现也较差。 AgCC 患者在学习试验中表现不佳,以及各种形式的延迟记忆缺陷,表明胼胝体促进大脑半球间的言语信息加工和编码。
The role of interhemispheric interactions in the encoding, retention, and retrieval of verbal memory can be clarified by assessing individuals with complete or partial agenesis of the corpus callosum (AgCC), but who have normal intelligence. This study assessed verbal learning and memory in AgCC using the California Verbal Learning Test—Second Edition (CVLT-II). Twenty-six individuals with AgCC were compared to 24 matched controls on CVLT-II measures, as well as Donders’ four CVLT-II factors (i.e., Attention Span, Learning Efficiency, Delayed Memory, and Inaccurate Memory). Individuals with AgCC performed significantly below healthy controls on the Delayed Memory factor, confirmed by significant deficits in short and long delayed free recall and cued recall. They also performed less well in original learning. Deficient performance by individuals with AgCC during learning trials, as well as deficits in all forms of delayed memory, suggest that the corpus callosum facilitates interhemispheric elaboration and encoding of verbal information.
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