The role of co-occurring disruptive behavior in the clinical presentation of children and adolescents with anxiety in the context of autism spectrum disorders.
The role of co-occurring disruptive behavior in the clinical presentation of children and adolescents with anxiety in the context of autism spectrum disorders.
复制标题
共发生的破坏性行为在自闭症谱系障碍背景下焦虑的儿童和青少年的临床表现中的作用。
DOI：
10.1007/s10578-012-0294-1
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发表时间：
2012
影响因子：
2.9
通讯作者：
Murphy,TanyaK
中科院分区：
文献类型：
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作者：
Storch,EricA;Arnold,ElysseB;Jones,AnnaM;Ale,ChelseaM;Wood,JeffreyJ;Ehrenreich-May,Jill;Lewin,AdamB;Mutch,PJane;Murphy,TanyaK
本研究探讨了破坏性行为障碍（DBD）共病对87名患有自闭症谱系障碍（ASD）和临床显著焦虑的儿童和青少年的理论相关性的影响。相对于单纯患有ASD和焦虑的青少年，患有ASD、焦虑和DBD的参与者：（a）根据临床医生、父母和自我报告，呈现出明显更严重的焦虑症状;（B）更有可能被处方抗精神病药物，但不太可能接受额外的心理社会和教育干预;（c）经历了明显更大的功能障碍和家庭干扰。这些结果表明，在ASD和焦虑的背景下同时发生的DBD会增加症状严重程度和功能障碍的风险，并且可能与抗精神病药物处方增加有关。
This study explored the impact of disruptive behavior disorder (DBD) comorbidity on theoretically relevant correlates among 87 children and adolescents with autism spectrum disorders (ASD) and clinically significant anxiety. Relative to youth with ASD and anxiety alone, participants with ASD, anxiety, and DBD: (a) presented with significantly more severe anxiety symptoms per clinician-, parent-, and self-report; (b) were more likely to be prescribed antipsychotic medication but were no more likely to receive additional psychosocial and educational interventions; and (c) experienced significantly greater functional impairment and family interference. These results suggest that co-occurring DBD in the context of ASD and anxiety confers greater risk for heightened symptom severity and functional impairment, and may be linked with increased prescription of antipsychotic medication.