ROLE OF RIBOSOMES IN STREPTOMYCIN-ACTIVATED SUPPRESSION
ROLE OF RIBOSOMES IN STREPTOMYCIN-ACTIVATED SUPPRESSION
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DOI：
10.1073/pnas.54.4.1076
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发表时间：
1965-01-01
影响因子：
11.1
通讯作者：
BRECKENRIDGE, L
中科院分区：
文献类型：
--
作者：
ANDERSON, WF;GORINI, L;BRECKENRIDGE, L
Streptomycin (Sm)-resistant mutants have been isolated from a strain of Escherichia coli bearing a defective ornithine transcarbamylase phenotypically suppressible in the presence of Sm (OTCSSu)- Some of them remain competent and others become incompetent for the Sm-activated suppression of the OTCSSu defect. Within each class the imposition of further auxotrophic mutations yields strains that are competent for the Sm-activated suppression of some of these additional mutations. In vivo these strains have different responses to one type of genetic suppressor. Ribosomes isolated from these different strains have been shown to differ in their response to the misreading action of Sm.
