Hyperoxia and human performance: a brief review.
Hyperoxia and human performance: a brief review.
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高氧和人类表现：简要回顾。
DOI：
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发表时间：
1982
影响因子：
4.1
通讯作者：
H. Welch
中科院分区：
文献类型：
--
作者：
H. Welch
本综述的目的是研究高氧气体混合物对人体性能的影响。证据似乎很清楚，当运动期间吸入富含氧气的气体时，表现会得到增强;然而，导致这种改善的生理机制仍然不清楚。增加的压力对性能有不利影响，因此，如果目的是了解增加的PO 2的影响，使用高压氧的研究是模糊的。文献中报道的高氧时最大O2摄取量的大幅增加可能是错误的，因为当使用O2分数升高的气体时，道格拉斯袋技术会遇到问题。这些明显的增加不容易与发表的高氧运动期间心输出量和血气浓度值相一致。PO 2升高的影响显然是广泛的，在一定程度上是独立的;这些影响包括对肺通气、血管平滑肌和细胞代谢的影响。现有的数据并不强有力地支持这一假设，即氧气输送的改善是高氧性能增强的原因。高氧对肺运动反应和酸碱反应均有影响。有证据表明，这些机制中的一个或两个可能在高氧的性能变化中发挥重要作用。
The intent of this review was to examine the effects of hyperoxic gas mixtures on human performance. The evidence seems clear that performance is enhanced when O2-enriched gases are inhaled during exercise; however, the physiological mechanisms responsible for the improvement remain obscure. Increased pressure has a detrimental effect on performance, so that studies using hyperbaric oxygenation are ambiguous if the intent is to understand the effects of increased PO2. The large increases in maximal O2 uptake with hyperoxia reported in the literature may be erroneous because of problems encountered with the Douglas bag technique when gases with elevated O2 fractions are used. These apparent increases cannot be easily reconciled with published values for cardiac output and blood gas concentrations during exercise with hyperoxia. The effects of elevated PO2 are apparently widespread and, to a degree, independent; these include effects on pulmonary ventilation, on vascular smooth muscle, and on cellular metabolism. The available data do not lend strong support to the hypothesis that improvement in O2 delivery is responsible for the enhanced performance with hyperoxia. There are effects of hyperoxia on the pulmonary responses to exercise and on the acid-base responses. There is evidence that one or both of these mechanisms could play an important role in the changes in performance with hyperoxia.