Cervical mucus monitoring prevalence and associated fecundability in women trying to conceive
Cervical mucus monitoring prevalence and associated fecundability in women trying to conceive
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DOI：
10.1016/j.fertnstert.2013.06.002
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发表时间：
2013-10-01
影响因子：
6.7
通讯作者：
Steiner, Anne Z.
中科院分区：
文献类型：
--
作者：
Evans-Hoeker, Emily;Pritchard, David A.;Steiner, Anne Z.
目标：评估宫颈粘液监测（CMM）在试图怀孕的女性中的应用，并确定监测是否与周期特异性受孕概率增加相关设计：妊娠时间队列研究。设置：基于人群的队列。患者：331名年龄在30 - 44岁之间，没有已知不孕症的尝试怀孕的妇女。干预：无。主要结果测量：CMM患病率和生育能力。结果：在研究的第一个周期中，20名女性（6%）一致地进行了CMM（在> 66%的相关周期日进行检查），60名女性（18%）不一致地进行了CMM（34%至66%的天数），73名女性（22%）很少进行CMM（33%的天数），178名女性（54%）没有进行CMM。在调整了年龄、种族、既往妊娠、体重指数、性交频率和尿促黄体激素（LH）监测后，持续进行CMM的周期在统计学上更有可能导致受孕。受孕能力也增加了一致性的CMM. Conclusions（S）：在妇女试图怀孕，CMM是不常见的，但我们的研究表明，CMM-一个自由的，自我导向的方法来确定可育窗口-是与独立的性交频率或使用尿LH监测增加受孕能力。（Fertil Steril（R）2013;100：1033-8. (C)2013年美国生殖医学会。）
Objective: To assess the use of cervical mucus monitoring (CMM) in women trying to conceive and determine whether monitoring is associated with increased cycle-specific probability of conception (fecundability).Design: Time-to-pregnancy cohort study.Setting: Population-based cohort.Patient(s): Three hundred thirty-one women trying to conceive, ages 30 to 44 years, without known infertility.Intervention(s): None.Main Outcome Measure(s): CMM prevalence and fecundability.Result(s): During the first cycle of the study, CMM was performed consistently (checked on > 66% of pertinent cycle days) by 20 women (6%), inconsistently (34% to 66% of days) by 60 women (18%), infrequently (% 33% of days) by 73 women (22%), and not performed by 178 women (54%). Cycles in which CMM was consistently performed were statistically significantly more likely to result in conception after adjusting for age, race, previous pregnancy, body mass index, intercourse frequency, and urinary luteinizing hormone (LH) monitoring. Fecundability also increased with increasing consistency of CMM.Conclusion(s): Among women trying to conceive, CMM is uncommon, but our study suggests that CMM-a free, self-directed method to determine the fertile window-is associated with increased fecundability independent of intercourse frequency or use of urinary LH monitoring. (Fertil Steril (R) 2013;100:1033-8. (C) 2013 by American Society for Reproductive Medicine.)