The contribution of blood flow to the skin temperature responses during a cold sensitivity test
The contribution of blood flow to the skin temperature responses during a cold sensitivity test
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DOI：
10.1007/s00421-013-2678-8
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发表时间：
2013-09-01
影响因子：
3
通讯作者：
Tipton, Michael
中科院分区：
文献类型：
--
作者：
Davey, Martha;Eglin, Clare;Tipton, Michael
用于寒冷损伤的冷敏感性试验（CST）中的假设是，观察到的皮肤温度（T（sk））反映了局部寒冷挑战后血流返回肢体。我们对这一假设提出了质疑。六名非冻伤的参与者在30 A摄氏度的空气中进行了两次CST。对照组（CON）CST包括12分钟的温和运动，然后将脚浸入15 A摄氏度的水中2分钟，然后进行15分钟的自发复温。闭塞（OCC）CST是相同的，除了在复温期间阻塞了流向足部的血流。将这些结果与6名非冷冻性寒冷损伤和中度-重度冷敏感（CS）个体的CST以及非灌注人类手指模型（NPDM）进行比较。浸泡前，CON和OCC条件下的大脚趾皮肤血流量（SkBF）相似[255（107）个激光多普勒单位（LDU）]，高于CS [59（52）个LDU]。复温期间，CON中的SkBF恢复到浸泡前值的104%，高于OCC和CS。浸泡前，CS [28.5（2.1）A ℃]中的大脚趾T（sk）低于CON [34.7（0.4）A ℃]、OCC [34.6（0.9）A ℃]和NPDM [35.0（0.4）A ℃]。在OCC中复温皮肤/表面温度期间，CS和NPDM相似并且均低于CON。在CST期间，SkBF确实有助于皮肤复温曲线，因为与OCC或NPDM相比，CON中观察到更快的复温速率。CS中较低的T（sk）可能是由于基础SkBF降低。
The presumption in a cold sensitivity test (CST) used for cold injuries is that the skin temperature (T (sk)) observed reflects the return of blood flow to the extremity following a local cold challenge. We questioned this assumption.Six non-cold injured participants undertook two CSTs in 30 A degrees C air. The control (CON) CST involved 12 min gentle exercise prior to immersing the foot into 15 A degrees C water for 2 min followed by 15 min of spontaneous rewarming. The occlusion (OCC) CST was the same except that blood flow to the foot was occluded during the rewarming period. These results were compared to CSTs from six individuals with non-freezing cold injury and moderate-severe cold sensitivity (CS) and a non-perfused human digit model (NPDM).Before immersion, great toe skin blood flow (SkBF) was similar in CON and OCC conditions [255 (107) laser Doppler units (LDU)] and was higher than CS [59 (52) LDU]. During rewarming, SkBF in CON returned to 104 % of the pre-immersion value and was higher than both OCC and CS. Great toe T (sk) before immersion was lower in CS [28.5 (2.1) A degrees C] compared to CON [34.7 (0.4) A degrees C], OCC [34.6 (0.9) A degrees C] and NPDM [35.0 (0.4) A degrees C]. During rewarming skin/surface temperature in OCC, CS and NPDM were similar and all lower than CON.SkBF does contribute to the skin rewarming profile during a CST as a faster rate of rewarming was observed in CON compared to either OCC or NPDM. The lower T (sk) in CS may be due to a reduced basal SkBF.