Metal-controlled Reversal of Enantioselectivity in Catalyzed Asymmetric Ring-opening Reactions of meso-Epoxides in Water
Metal-controlled Reversal of Enantioselectivity in Catalyzed Asymmetric Ring-opening Reactions of meso-Epoxides in Water
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DOI：
10.1246/cl.2009.904
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发表时间：
2009-09-05
影响因子：
1.6
通讯作者：
Kobayashi, Shu
中科院分区：
文献类型：
--
作者：
Kokubo, Masaya;Naito, Takeshi;Kobayashi, Shu
Reversal of enantioselectivity in Cu-chiral bipyridine catalyzed asymmetric ring-opening reactions of meso-epoxides with indole and aniline derivatives was observed compared to Sc-chiral bipyridine catalyzed reactions, where the same chiral ligand was used. It was revealed from X-ray crystal structural analysis that a square pyramidal structure for the Cu(II) complex and a pentagonal bipyramidal structure for the Sc(III) complex were formed, which could explain the reversal of the enantioselectivity.
