PRESBYOPIA AND VELOCITY OF SOUND IN THE LENS
PRESBYOPIA AND VELOCITY OF SOUND IN THE LENS
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DOI：
10.1097/00006324-199404000-00004
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发表时间：
1994-04-01
影响因子：
1.4
通讯作者：
VANDERHEIJDE, GL
中科院分区：
文献类型：
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作者：
BEERS, APA;VANDERHEIJDE, GL
透镜物质的弹性随年龄而改变，这有助于老视。透镜物质弹性的变化可能是水和可溶性蛋白质变化的结果（1）或透镜纤维细胞骨架和膜变化的结果（2）。如果它是由（1）引起的，那么声音在透镜中的速度应该随着年龄而变化。如果它是由（2）引起的，则声音在透镜中的速度不会改变。使用连续超声生物测量技术，在一组24名年龄在15至45岁的健康受试者中测量透明晶状体中的声速，视力为6/6或更好。在这组中，最大振幅随年龄的增长而下降。结果发现，尽管发生老花眼，声速不随年龄的变化。我们的研究结果支持这一假设，即年龄相关的变化，在透镜纤维细胞骨架和膜负责的变化，弹性性能的透镜的问题，从而有助于老视。
The elastic properties of lens matter change with age and this contributes to presbyopia. The changes in elasticity of lens matter could be the result of a change in water and soluble proteins (1) or a change in lens fiber cytoskeleton and membranes (2). If it is caused by (1) then the velocity of sound in the lens should change with age. If it is caused by (2) the velocity of sound in the lens will not change. Using the technique of continuous ultrasonographic biometry, the velocity of sound in clear lenses was measured in vivo in a group of 24 healthy subjects aged 15 to 45 years with a visual acuity of 6/6 or better. In this group maximum accommodative amplitude decreased with age. It was found that, despite the occurrence of presbyopia, the velocity of sound did not change with age. Our results support the hypothesis that age-related changes in lens fiber cytoskeleton and membranes are responsible for the change in elastic properties of lens matter and thus contribute to presbyopia.