Only self-paced mating is rewarding in rats of both sexes
Only self-paced mating is rewarding in rats of both sexes
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DOI：
10.1006/hbeh.2001.1712
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发表时间：
2001-12-01
影响因子：
3.5
通讯作者：
Paredes, RG
中科院分区：
文献类型：
--
作者：
Martínez, I;Paredes, RG
当老鼠在传统的交配室（一只雄性和一只雌性）中交配时，雄性决定交配顺序的节奏，雄性会形成一种奖励状态，通过条件性位置偏好（CPP）来评估。在这种交配情况下，雌性不会产生奖励状态。然而，当雌性大鼠能够控制（节奏）性刺激的速度，从而减少与交配相关的厌恶后果时，就会观察到明显的 CPP。在本研究中，CPP 范式用于确定当雌性大鼠调整性互动节奏时，雄性大鼠性交互动诱导的强化状态是否可以维持。成年雄性和雌性大鼠在两种不同条件之一下交配：（1）受试者能够调整其性交互动的节奏，或（2）受试者无法调整其性接触的节奏。结果表明，当雄性能够控制性互动时，它们会产生明显的地点偏好，而与调整性交接触节奏的雌性交配的雄性则不会产生 CPP。同样，只有能够控制性接触节奏的女性才会产生位置偏好。这些结果表明，男性和女性的性交互动只有当他们能够控制性互动时才能诱导奖赏状态。在半自然条件下，老鼠的性行为是高度杂乱的，它们成群交配，并在交配过程中反复更换伴侣。这种行为序列允许男性和女性控制性互动的速率，确保奖赏状态的诱导比性交反应的实际表现更持久。 (C) 2001 年爱思唯尔科学。
When rats are mated in a traditional mating chamber (with one male and one female) in which the male dictates the pace of the copulatory sequence, males develop a reward state as evaluated by conditioned place preference (CPP). In this mating situation no reward state is induced in females. However, when female rats are able to control (pace) the rate of sexual stimulation, thereby reducing the aversive consequences associated with mating, a clear CPP is observed. In the present study the CPP paradigm was used to determine whether if the reinforced state induced by coital interactions in male rats can be maintained when females pace the sexual interaction. Adult male and female rats were mated in one of two different conditions: (1) where subjects were able to pace their coital interactions or (2) where subjects were not able to pace their sexual contacts. The results showed that when males had control over the sexual interaction they developed a clear place preference while males that mated with females that paced their coital contacts did not develop CPP. Similarly, only females that were able to pace their sexual contacts developed place preference. These results suggest that coital interactions in males, as well as in females, can induce a reward state only when they are able to control the sexual interaction. Under seminatural conditions sexual behavior in rats is highly promiscuous, they mate in groups and repeatedly change partners in the middle of copulation. This behavioral sequence allows both, male and female to control the rate of sexual interaction, assuring the induction of a reward state outlasting the actual performance of coital responses. (C) 2001 Elsevier Science.