ACID PROFILES AND PH OF CARIOUS DENTIN IN ACTIVE AND ARRESTED LESIONS
ACID PROFILES AND PH OF CARIOUS DENTIN IN ACTIVE AND ARRESTED LESIONS
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DOI：
10.1177/00220345940730121001
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发表时间：
1994-12-01
影响因子：
7.6
通讯作者：
YAMADA, T
中科院分区：
文献类型：
--
作者：
HOJO, S;KOMATSU, M;YAMADA, T
龋损中的有机酸在龋病的发生和发展中起重要作用。我们研究了牙本质龋的临床类型与酸剖面或病变的pH值之间的关系。将76颗恒牙的牙本质龋损分为活动型、停滞型、修复体下型和未分类型。龋坏牙本质pH值明显低于健康牙本质（P < 0.001）。高乳酸盐含量的龋坏牙本质的pH值低于高乙酸盐和丙酸盐含量的龋坏牙本质的pH值（p < 0.001）。活动性病变牙本质的平均pH值为4.9，主要酸为乳酸（平均百分比为88.2）。相比之下，龋性牙本质从逮捕病变表现出较高的pH值，5.7，与乙酸和丙酸为主导的酸（乙酸和丙酸的平均百分比，分别为64.0和18.2）。酸配置文件（乙酸和丙酸的平均百分比，分别为54.0和27.7）和pH值（平均5.8）的龋性牙本质从病变下的修复采样是类似的牙本质从逮捕病变。这项研究表明，牙本质龋的临床分类和酸剖面和pH值之间有明确的关系，这两个因素是重要的牙本质龋的病因。
Organic acids in caries lesions play important roles in initiation and progress of dental caries. We investigated relationships between clinical types of dentin caries and acid profile or pH in the lesions. Caries lesions in dentin from 76 permanent teeth were classified into active, arrested, situated beneath a restoration, and unclassified types. The pH of carious dentin was distinctly lower than that of sound dentin (p < 0.001). Carious dentin with a high percentage of lactate had a lower pH than that with a high percentage of acetate and propionate (p < 0.001). Dentin from active lesions showed a mean pH of 4.9, and the dominant acid was lactate (mean percentage, 88.2). In contrast, carious dentin from arrested lesions showed a higher pH, 5.7, with acetate and propionate as the dominant acids (mean percentages of acetate and propionate, 64.0 and 18.2, respectively). The acid profile (mean percentages of acetate and propionate, 54.0 and 27.7, respectively) and pH (mean 5.8) of carious dentin sampled from lesions beneath a restoration were similar to those of dentin from arrested lesions. This study showed a clear relationship between clinical classification of dentin caries and acid profile and pH, suggesting that both factors are important in dentin caries etiology.