Motivational and emotional influences on cognitive control in depression: A pupillometry study.
Motivational and emotional influences on cognitive control in depression: A pupillometry study.
复制标题
DOI：
10.3758/s13415-014-0323-6
复制
发表时间：
2015-06
期刊：
影响因子：
--
通讯作者：
Mandell D
中科院分区：
文献类型：
--
作者：
Jones NP;Siegle GJ;Mandell D
Depressed people perform poorly on cognitive tasks, however under certain conditions they show intact cognitive performance with physiological reactivity consistent with needing to recruit additional cognitive control. We hypothesize that this apparent compensation is driven by the presence of affective processes (e.g., state anxiety) which in turn are moderated by the depressed individual’s motivational state. Clarifying these processes may help researchers identify targets for treatment that if addressed may improve depressed patients’ cognitive functioning. To test this hypothesis, 36 participants with unipolar depression and 36 never-depressed controls completed a problem-solving task modified to elicit anxiety. Participants completed measures of motivation, anxiety, sadness, and rumination, while pupillary responses were continuously measured during problem-solving as an index of cognitive control. Anxiety increased throughout the task for all participants, while both sadness and rumination were decreased during the task. In addition, anxiety more strongly affected planning accuracy in depressed participants relative to controls, regardless of participants’ levels of motivation. In contrast, differential effects of anxiety on pupillary responses were observed as a function of depressed participants’ levels of motivation. Consistent with behavioral results, less-motivated and anxious depressed participants demonstrated smaller pupillary responses, whereas more highly-motivated and anxious depressed participants demonstrated larger pupillary responses than controls. Strong effects of sadness and rumination on cognitive control in depression were not observed. Thus, we conclude that anxiety inhibits the recruitment of cognitive control in depression and that a depressed individual’s motivational state determines, in part, whether they are able to compensate by recruiting additional cognitive control.
登录
查看更多内容
影响因子：
3.8
作者：
Chiew KS;Braver TS
通讯作者：
Braver TS
影响因子：
5.7
作者：
Harvey, PO;Fossati, P;Dubois, B
通讯作者：
Dubois, B
影响因子：
3.7
作者：
Granholm, E;Asarnow, RF;Dykes, KL
通讯作者：
Dykes, KL
影响因子：
6.9
作者：
Elliott, R;Baker, SC;Sahakian, BJ
通讯作者：
Sahakian, BJ
影响因子：
5.4
作者：
Deckersbach, Thilo;Rauch, Scott L.;Dougherty, Darin D.
通讯作者：
Dougherty, Darin D.