Using a smartphone app in changing cardiovascular risk factors: A randomized controlled trial (EVIDENT II study)
Using a smartphone app in changing cardiovascular risk factors: A randomized controlled trial (EVIDENT II study)
复制标题
DOI：
10.1016/j.ijmedinf.2019.02.004
复制
发表时间：
2019-05-01
影响因子：
4.9
通讯作者：
Iturregui-San Nicolas, Eguskine
中科院分区：
文献类型：
--
作者：
Gonzalez-Sanchez, Jesus;Recio-Rodriguez, Jose, I;Iturregui-San Nicolas, Eguskine
背景和目的：在过去的几年里，出现了许多旨在改善健康的移动的应用程序，但分析其对心血管风险因素（CVRF）有效性的研究却很少。我们的目的是评估对CVRF的影响，如高血压，血脂异常，糖尿病和全球CVR，增加使用智能手机应用程序的干预，包括对体力活动和地中海diet.Method的标准咨询：这是一项多中心，随机和对照的临床试验。从2014年1月至2016年9月，通过随机抽样从6家卫生中心共选择了833名受试者参与。其中，415人被分配到咨询+应用程序组（IG），418人被分配到咨询组（CG）。IG还接受了使用移动的应用程序的培训。主要结局是IG与CG相比，在3个月和12个月时CVRF和估计CVR的变化。结果：在3个月或12个月时未观察到CVR的显著变化。然而，在一些CVRFS中，观察到组间效应有利于12个月时的CG：SBP、DBP、总胆固醇和甘油三酯：2.02 mmHg（95% CI：0.43-3.61），1.21 mmHg（95% CI：0.20-2.24），5.24 mg/dl（95% CI：1.22-9.26）和7.24 mg/dl（95% CI：0.53-14.32）。在饮食和体育活动的标准咨询中增加了三个月使用应用程序的干预，从长期来看，未提供改善CVRF或估计CVR的额外获益。
Background and objective: The last few years have seen the appearance many mobile applications aimed at improving health, but studies analyzing their effectiveness on cardiovascular risk factors (CVRFs) are few and far between. Our aim was to assess the effect on CVRFs such as hypertension, dyslipidemia, diabetes and global CVR, of adding the use of a smartphone app to an intervention consisting of standard counseling on physical activity and the Mediterranean diet.Method: This is a multicenter, randomized and controlled clinical trial. From January 2014 and September 2016, a total of 833 subjects selected by random sampling from six health centers participated. Of these, 415 were assigned to the counseling + app group (IG) and 418 to the counseling only group (CG). The IG additionally received training in the use of a mobile application. The main outcome was the change in CVRFs and estimated CVR at 3 and 12 months in the IG compared to the CG.Results: No significant changes were observed at 3 or 12 months in terms of CVR. Nevertheless, an effect between groups was observed in favor of the CG at 12 months in some CVRFS: SBP, DBP, total cholesterol and triglycerides: 2.02 mmHg (95% CI: 0.43-3.61), 1.21 mmHg (95% CI: 0.20-2.24), 5.24 mg/dl (95% CI: 1.22-9.26) and 7.24 mg/dl (95% CI: 0.53-14.32).Conclusion: Adding an intervention with the use of an app for three months to standard counseling on diet and physical activity, does not provide additional benefits for improving CVRFs or the estimated CVR in the long term.