The Acute Asthma Severity Assessment Protocol (AASAP) study: objectives and methods of a study to develop an acute asthma clinical prediction rule.
The Acute Asthma Severity Assessment Protocol (AASAP) study: objectives and methods of a study to develop an acute asthma clinical prediction rule.
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DOI：
10.1136/emj.2010.110957
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发表时间：
2012-06
期刊：
影响因子：
--
通讯作者：
Hartert TV
中科院分区：
文献类型：
--
作者：
Arnold DH;Gebretsadik T;Abramo TJ;Sheller JR;Resha DJ;Hartert TV
急性哮喘加重是儿科急诊科（PED）就诊和住院的最常见原因之一，复发经常需要重复紧急护理。虽然有护理计划，但没有急性哮喘预测规则（APR）来评估严重程度和预测结果。急性哮喘严重程度评估方案（AASAP）研究的主要目的是为儿科患者的急性哮喘加重制定多变量APR。我们正在招募一个前瞻性的，方便的样本，年龄在5至17岁的急性哮喘急性发作谁目前的城市，学术，三级PED。研究方案和数据分析计划符合临床预测规则开发的公认生物统计学和临床标准。一旦累积了1，500的整个样本量，将进行APR建模。我们预计，APR将提高急诊科的资源利用率，有助于疾病评估的标准化，并允许医生和非医生提供者参与早期的客观决策。本报告旨在描述AASAP研究的研究目的和详细方法。
Acute asthma exacerbations are one of the most common reasons for pediatric emergency department (PED) visits and hospitalizations, and relapse frequently necessitates repeat urgent care. While care plans exist, there are no acute asthma prediction rules (APR)to assess severity and predict outcome. The primary objective of the Acute Asthma Severity Assessment Protocol (AASAP) study is to develop a multivariable APR for acute asthma exacerbations in the pediatric patient. We are enrolling a prospective, convenience sample aged 5 to 17 years with acute asthma exacerbations who present to an urban, academic, tertiary PED. The study protocol and data analysis plan conform to accepted biostatistical and clinical standards for clinical prediction rule development. Modeling of the APR will be performed once the entire sample size of 1,500 has accrued. We anticipate that the APR will improve resource utilization in the emergency department, aid in standardization of disease assessment, and allow physician and non-physician providers to participate in earlier objective decision making. The objective of this report is to describe the study objectives and detailed methodology of the AASAP study.
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影响因子：
9.3
作者：
Bossuyt, PM;Reitsma, JB;de Vet, HCW
通讯作者：
de Vet, HCW
影响因子：
2
作者：
HARRELL, FE;LEE, KL;ROSATI, RA
通讯作者：
ROSATI, RA
DOI：
10.1164/rccm.200406-710st
发表时间：
2005-04-15
影响因子：
24.7
作者：
American Thoracic Society;European Respiratory Society
通讯作者：
European Respiratory Society
影响因子：
5.1
作者：
Chalut, DS;Ducharme, FM;Davis, GM
通讯作者：
Davis, GM
影响因子：
3.1
作者：
Hadjikoumi, I;Hassan, A;Milner, AD
通讯作者：
Milner, AD