Persistent Breast Pain Among Women With Histories of Breast-conserving Surgery for Breast Cancer Compared With Women Without Histories of Breast Surgery or Cancer
Persistent Breast Pain Among Women With Histories of Breast-conserving Surgery for Breast Cancer Compared With Women Without Histories of Breast Surgery or Cancer
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DOI：
10.1097/ajp.0000000000000377
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发表时间：
2017-01-01
影响因子：
2.9
通讯作者：
Bovbjerg, Dana H.
中科院分区：
文献类型：
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作者：
Edmond, Sara N.;Shelby, Rebecca A.;Bovbjerg, Dana H.
目的：本研究比较了接受保乳手术的乳腺癌患者和无乳腺癌病史的女性持续乳房疼痛。方法：招募乳腺癌幸存者（n=200）进行首次术后监测乳房x光检查（术后6至15个月）。无乳腺癌病史的妇女（n=150）在常规乳房x光检查时被招募。所有女性都完成了乳房疼痛、疼痛对日常活动和亲密关系的干扰、对乳房疼痛的担忧、焦虑症状和抑郁症状的测量。还收集了人口和医疗信息。结果：46.5%的乳腺癌幸存者和12.7%无乳腺癌病史的女性报告持续性乳房疼痛（持续时间>= 6个月）（P= 3/10），以及更高的平均乳房疼痛强度和不愉快评分。与没有持续乳房疼痛的幸存者或没有乳腺癌病史的女性相比，患有持续性乳房疼痛的乳腺癌幸存者明显有更高水平的抑郁症状，以及对疼痛的担忧和干扰。与没有乳腺癌病史的女性相比，持续乳房疼痛的乳腺癌幸存者的焦虑症状明显更高。讨论：结果表明，与没有保乳手术史的女性相比，持续乳房疼痛对有保乳手术史的女性有负面影响。应该探索改善持续性乳房疼痛和改善持续性乳房疼痛妇女适应的策略，并将其纳入乳腺癌幸存者的标准护理。
Objectives: This study compared persistent breast pain among women who received breast-conserving surgery for breast cancer and women without a history of breast cancer.Methods: Breast cancer survivors (n=200) were recruited at their first postsurgical surveillance mammogram (6 to 15mo post-surgery). Women without a breast cancer history (n=150) were recruited at the time of a routine screening mammogram. All women completed measures of breast pain, pain interference with daily activities and intimacy, worry about breast pain, anxiety symptoms, and depression symptoms. Demographic and medical information were also collected.Results: Persistent breast pain (duration >= 6 mo) was reported by 46.5% of breast cancer survivors and 12.7% of women without a breast cancer history (P= 3/10), as well as higher average breast pain intensity and unpleasantness scores. Breast cancer survivors with persistent breast pain had significantly higher levels of depressive symptoms, as well as pain worry and interference, compared with survivors without persistent breast pain or women without a breast cancer history. Anxiety symptoms were significantly higher in breast cancer survivors with persistent breast pain compared with women without a breast cancer history.Discussion: Results indicate that persistent breast pain negatively impacts women with a history of breast-conserving cancer surgery compared with women without that history. Strategies to ameliorate persistent breast pain and to improve adjustment among women with persistent breast pain should be explored for incorporation into standard care for breast cancer survivors.