Biogenic amines and depression. Biochemical and pharmacological separation of two types of depression.
Biogenic amines and depression. Biochemical and pharmacological separation of two types of depression.
复制标题
生物胺和抑郁症。
作者：
J. Maas
最近的研究结果表明，抑郁症可以分为两组，A和B，使用特定的生物化学和药理学标准。提示A组存在去甲肾上腺素系统紊乱，但无改变。此外，B型患者可能患有5-羟色胺障碍，而不是去甲肾上腺素或多巴胺系统障碍。人类抑郁症的这种生物化学异质性对研究者和临床医生都有影响，并可能解释情感障碍患者生物学研究中的不同发现。
Recent research findings indicate that depressive disorders may be divided into two groups, A and B, using specific biochemical and pharmacological criteria. It is suggested that in the A group there is a disorder of norepinephrine systems are not altered. Further, there is the possibility that B types patients have disorder of serotonin, but not norepinephrine or dopamine systems. This biochemical heterogeneity of human depression has implications for both investigators and clinicians, and may account for disparate findings in biological studies of patients with affective disorders.