Efficacy of psychoeducation on symptomatic and functional recovery in bipolar disorder
Efficacy of psychoeducation on symptomatic and functional recovery in bipolar disorder
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DOI：
10.1111/acps.12007
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发表时间：
2013-02-01
影响因子：
6.7
通讯作者：
Moreno, R. A.
中科院分区：
文献类型：
--
作者：
de Barros Pellegrinelli, K.;Costa, L. F. de O.;Moreno, R. A.
目的：评价心理教育对双相情感障碍（BD）患者症状和功能恢复以及生活质量（QoL）的疗效。方法：55例BD Ⅰ、Ⅱ期缓解期患者（Young躁狂量表6分，汉密尔顿抑郁量表7分）。门诊患者被匹配分配接受16次心理教育[实验组（EG）]或16次安慰剂不接受心理教育[对照组（CG）]。在研究基线、中点、终点以及6个月和12个月随访时对各组进行评价。结果如下：除了EG受试者主观感知的总体临床改善外，两组间评价的变量（情绪症状、功能和生活质量）无显著差异。两组均显示出改善临床总体印象和QoL（环境）的趋势。没有观察到情绪症状减轻或心理社会功能改善。心理社会治疗依从性与整体功能、社会适应、社交能力和整体临床印象呈正相关。结论：十六次心理教育对于预防双相情感障碍患者的情绪发作或改善功能似乎无效。
Objective: To evaluate the efficacy of psychoeducation in the symptomatic and functional recovery, and quality of life (QoL) in a sample of patients with bipolar disorder (BD). Method: The sample comprised 55 patients with BD I and II in remission (Young Mania Rating Scale =6 and Hamilton Depression Rating Scale =7). Out-patients were matched assigned to receive 16 sessions of psychoeducation [experimental group (EG)] or 16 sessions of placebo without psychoeducation [control group (CG)]. Groups were evaluated at study baseline, midpoint, endpoint, and at 6- and 12-month follow-ups. Results: No significant differences between the groups were found for the variables evaluated (mood symptoms, functioning and QoL), except for overall clinical improvement, subjectively perceived by EG subjects. Both groups showed a trend toward improved clinical global impression and QoL (environmental). No reduction in mood symptoms or improvement in psychosocial functioning was observed. Psychosocial treatment compliance was positively correlated with global functioning, social adjustment, sociability, and global clinical impression. Conclusion: Sixteen session psychoeducation seems to be ineffective to prevent mood episodes or improve functioning in a sample of bipolar patients.