RICE BRAN OIL LOWERS SERUM TOTAL AND LOW-DENSITY-LIPOPROTEIN CHOLESTEROL AND APO-B LEVELS IN NONHUMAN-PRIMATES
RICE BRAN OIL LOWERS SERUM TOTAL AND LOW-DENSITY-LIPOPROTEIN CHOLESTEROL AND APO-B LEVELS IN NONHUMAN-PRIMATES
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DOI：
10.1016/0021-9150(91)90075-e
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发表时间：
1991-06-01
期刊：
影响因子：
5.3
通讯作者：
HEGSTED, DM
中科院分区：
文献类型：
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作者：
NICOLOSI, RJ;AUSMAN, LM;HEGSTED, DM
在非人灵长类动物中研究了米糠油（RBO）的降血脂反应，这些动物饲喂含有0- 35%Kcal米糠油作为膳食脂肪的油混合物的半纯化饲料。研究表明：（a）血清总胆固醇（TC）和低密度脂蛋白胆固醇（LDLC）的降低程度与稳定饮食猴的初始血清胆固醇水平高度相关;（B）日粮中米糠油含量是影响血清TC的主要因素，LDLC和apoB导致LDLC降低高达40%，而不影响高密度脂蛋白胆固醇（HDLC）时，RBO是唯一的膳食油喂养;（c）RBO的胆固醇降低能力不能解释其脂肪酸组成。这些研究表明，RBO可能是一种额外的植物油，通过独特的机制降低血清胆固醇水平，这需要进一步研究。
The hypolipidemic response of rice bran oil (RBO) was investigated in nonhuman primates fed semi-purified diets containing blends of oils which included RBO at 0-35% Kcals as dietary fat. The studies demonstrated the following: (a) the degree of reduction of serum total cholesterol (TC) and low density lipoprotein cholesterol (LDLC) was highly correlated with initial serum cholesterol levels of the monkey on the stabilization diet; (b) the content of rice bran oil in the diet was the predominant factor influencing serum TC, LDLC and apoB causing up to a 40% reduction in LDLC without affecting high density lipoprotein cholesterol (HDLC) when RBO was the sole dietary oil fed; (c) the cholesterol-lowering capabilities of RBO were not explained by its fatty acid composition. These studies suggest that RBO may be an additional vegetable oil which lowers serum cholesterol levels by unique mechanisms which will require further study.