rbamtools: an R interface to samtools enabling fast accumulative tabulation of splicing events over multiple RNA-seq samples
rbamtools: an R interface to samtools enabling fast accumulative tabulation of splicing events over multiple RNA-seq samples
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DOI：
10.1093/bioinformatics/btu846
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发表时间：
2015-05-15
期刊：
影响因子：
5.8
通讯作者：
Schwender, Holger
中科院分区：
文献类型：
--
作者：
Kaisers, Wolfgang;Schaal, Heiner;Schwender, Holger
开源环境R是最广泛使用的软件，用于统计探索生物数据集，包括序列比对。BAM是用于序列比对的事实上的标准文件格式。使用rbamtools，我们现在为R用户提供了一个完整的BAM访问范围，例如阅读，写入，子集提取和对齐深度绘图，其中脚本语法严格遵循SAM/BAM格式。此外，rbamtools还支持对多个BAM文件上的拼接事件进行快速累计制表。
The open source environment R isf the most widely used software to statistically explore biological data sets including sequence alignments. BAM is the de facto standard file format for sequence alignment. With rbamtools, we provide now a full spectrum of accessibility to BAM for R users such as reading, writing, extraction of subsets and plotting of alignment depth where the script syntax closely follows the SAM/BAM format. Additionally, rbamtools enables fast accumulative tabulation of splicing events over multiple BAM files.