Selenite nuclear cataract: review of the model.

Selenite nuclear cataract: review of the model.
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DOI：
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发表时间：
1997-07
期刊：
Molecular vision
影响因子：
2.2
通讯作者：
T. Shearer;Hong Ma;C. Fukiage;M. Azuma
T. Shearer;Hong Ma;C. Fukiage;M. Azuma
中科院分区：
医学4区
文献类型：
--
作者：
T. Shearer;Hong Ma;C. Fukiage;M. Azuma

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本文综述了亚硒酸盐过量白内障——幼鼠核性白内障的实验模型。主题包括白内障的产生和评估过程、晶状体上皮的代谢和分子变化、钙积累、钙活化蛋白酶系统的激活、晶体蛋白沉淀的机制、抗白内障药物测试以及与人类白内障的相关性。
Selenite overdose cataract, an experimental model of nuclear cataract produced in young rats is reviewed. Topics include procedures for cataract production and assessment, metabolic and molecular changes in the epithelium of the lens, calcium accumulation, activation of calcium-activated protease system, mechanisms for crystallin precipitation, anti-cataract drug testing and relevance to human cataract.