MOLECULAR MODEL-BUILDING BY COMPUTER
MOLECULAR MODEL-BUILDING BY COMPUTER
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DOI：
10.1038/scientificamerican0666-42
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发表时间：
1966-01-01
影响因子：
3
通讯作者：
LEVINTHAL, C
中科院分区：
文献类型：
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作者：
LEVINTHAL, C
现代生物学的许多问题都涉及生物功能和分子结构之间的详细关系。只有当人们了解了生物系统中所有分子成分的结构以及它们如何相互作用时，目前提出的一些问题才能得到完全的回答。当然，赛勒斯·列文塔尔在生物学中有许多问题，生物学家对此有一些见解，但他们还不能从分子结构的角度提出合适的问题。然而，随着他们对这些问题的认识越来越清楚，他们对结构信息的需求也越来越大。在我们麻省理工学院的实验室里，我们最近开始使用
Many problems of modern biology are concerned with the detailed relation between biological function and molecular structure. Some of the questions currently being asked will be completely answered only when one has an understanding of the struc ture of all the molecular components of a biological system and a knowledge of how they interact. There are, of course, by Cyrus Levinthal a large number of problems in biology into which biologists have some insight but concerning which they cannot yet ask suitable questions in terms of molec ular structure. As they see such prob lems more clearly, however, they in variably£ nd an increasing need for structural information. In our laboratory at the Massachusetts Institute of Tech nology we have recently started using a