THE STABILITY OF DEOXYNIVALENOL AND 3-ACETYL DEOXYNIVALENOL TO GAMMA-IRRADIATION
THE STABILITY OF DEOXYNIVALENOL AND 3-ACETYL DEOXYNIVALENOL TO GAMMA-IRRADIATION
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DOI：
10.1080/02652039309374143
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发表时间：
1993-03-01
期刊：
影响因子：
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通讯作者：
PATTERSON, MF
中科院分区：
文献类型：
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作者：
ONEILL, K;DAMOGLOU, AP;PATTERSON, MF
研究了脱氧雪腐烷醇和3-乙酰脱氧雪腐烷醇在不同条件下对co -60- γ辐射的稳定性。脱氧雪腐镰刀菌醇和3-乙酰脱氧雪腐镰刀菌醇分别在玉米上进行了水溶液和干态辐照。采用高效液相色谱法监测毒素的分解情况。脱氧雪腐镰刀菌醇和3-乙酰脱氧雪腐镰刀菌醇在水溶液中辐照比在玉米上辐照更敏感。脱氧雪腐镰刀菌醇和3-乙酰脱氧雪腐镰刀菌醇在水溶液中的分解分别在1 kGy和5 kGy时开始，在50 kGy时两种毒素都被完全破坏。当辐照在玉米上时，毒素仅在辐照至20千戈瑞后才开始分解，80 - 90%的毒素在辐照至50千戈瑞后仍然存在。毒素的照射没有引起对仓鼠肾细胞毒性增加的新化合物的形成。在干燥条件下辐照时，DON和3-A DON对50 kGy的辐照都是稳定的。使用低剂量γ辐照来破坏谷物上存在的预先形成的毒素似乎不是一种适合于脱氧雪腐镰刀菌醇和3-乙酰脱氧雪腐镰刀菌醇污染的谷物解毒的方法，因为破坏它们所需的辐照剂量很高（约50千戈瑞）。
The stability of deoxynivalenol and 3-acetyl deoxynivalenol to irradiation by Co-60-gamma radiation under various conditions was investigated. Deoxynivalenol and 3-acetyl deoxynivalenol were irradiated on maize, in aqueous solution and in the dry state. Breakdown of the toxins was monitored by high performance liquid chromatography. Both deoxynivalenol and 3-acetyl deoxynivalenol were more sensitive to irradiation when irradiated in aqueous solution than when irradiated on maize. Breakdown of deoxynivalenol and 3-acetyl deoxynivalenol in aqueous solution began at 1 kGy and 5 kGy respectively and both toxins were completely destroyed by 50 kGy. When irradiated on maize, breakdown of the toxins only began after irradiation to 20 kGy and 80 - 90% of the toxins remained after irradiation to 50 kGy. Irradiation of the toxins did not cause the formation of new compounds of increased toxicity to baby hamster kidney cells. Both DON and 3-A DON were stable to irradiation to 50 kGy when irradiated in the dry condition. The use of low dose gamma irradiation to destroy preformed toxins present on grain does not appear to be a suitable method for the detoxification of grain contaminated with deoxynivalenol and 3-acetyl deoxynivalenol because of the high irradiation dose that would be required for their destruction (>50 kGy).