Comparison of Donor Cornea Endothelial Cell Density Determined by Eye Banks and by a Central Reading Center in the Cornea Preservation Time Study.
Comparison of Donor Cornea Endothelial Cell Density Determined by Eye Banks and by a Central Reading Center in the Cornea Preservation Time Study.
复制标题
角膜保存时间研究中眼库和中央阅读中心测定的供体角膜内皮细胞密度的比较。
DOI：
10.1097/ico.0000000000001846
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发表时间：
2019
期刊：
影响因子：
2.8
通讯作者：
Lass,J
中科院分区：
文献类型：
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作者：
Benetz,BethAnn;Stoeger,ChristopherG;Patel,SanjayV;OʼBrien,RobertC;Szczotka-Flynn,LorettaB;Ayala,AllisonR;Maguire,MaureenG;Menegay,HarryJ;Bedard,Peter;Clover,JamesonM;Gupta,PankajC;McCoy,KristenE;Song,JonathanC;Lass,J
目的：评价眼库（EBs）和阅读中心在角膜保存时间研究中内皮细胞密度（ECD）测定的一致性。方法：角膜图像分析阅读中心（CIARC）对eb获得的术前中心内皮图像（在EBs剥离板层进行Descemet剥离自动内皮角膜移植术后或在手术前，如果外科医生准备好了）进行可变帧图像分析以确定ECD。EBs采用他们通常的ECD测定方法。CIARC和EBs还通过筛选EBs在供体评估期间拍摄的中心内皮图像提供ECD测定。两个独立的屏蔽CIARC读取器以测量平均值确定ECD。结果:
Purpose:To evaluate agreement between eye banks (EBs) and a reading center on endothelial cell density (ECD) determinations in the Cornea Preservation Time Study.Methods:The Cornea Image Analysis Reading Center (CIARC) performed variable frame image analysis on EB-obtained–preoperative central endothelial images (after lamellar dissection for Descemet stripping automated endothelial keratoplasty by the EBs or before shipping, if surgeon prepared) to determine ECD. The EBs performed their usual method of ECD determination. The CIARC and EBs also provided ECD determinations from screening central endothelial images taken by the EBs during donor evaluation. Two independent masked CIARC readers determined ECD with measurements averaged.Results: