Effect of portosystemic shunting on PGI2 and glucagon levels in humans.
Effect of portosystemic shunting on PGI2 and glucagon levels in humans.
复制标题
门体分流对人体 PGI2 和胰高血糖素水平的影响。
DOI：
10.1097/00000658-199303000-00006
复制
发表时间：
1993
影响因子：
9
通讯作者：
Cameron,JL
中科院分区：
文献类型：
--
作者：
Sitzmann,JV;Campbell,KA;Wu,Y;Cameron,JL
Objective•• This study determined if the proposed mediators of splanchnic blood flow, prostacyclin and glucagon, were elevated in patients with portal hypertension undergoing portal systemic shunts.Summary Background Data Chronic portal hypertension results in increased portal venous pressure and increased splanchnic blood flow. Animal studies have suggested prostacyclin or glucagon, potent vasodilators, as potential mediators of this increased flow. Correlative clinical studies have been difficult to perform due to the wide variation in degree of portal-systemic shunting and the frequent association of parenchymal liver disease in patients with cirrhosis.
