Evaluation of Temperature Distribution Around the Probe in Cryoablation of Lipiodol-Mixed-Tissue Phantom
Evaluation of Temperature Distribution Around the Probe in Cryoablation of Lipiodol-Mixed-Tissue Phantom
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DOI：
10.1007/s00270-020-02710-3
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发表时间：
2020-11-18
影响因子：
2.9
通讯作者：
Yamada，Kei
中科院分区：
文献类型：
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作者：
Yamashita，Masanori;Miura，Hiroshi;Yamada，Kei
PurposeTo determine whether alcohol，which has low thermal conductivity，influences ice ball formation during cryoablation of a alcohol-mixed-tissue phantom.Materials and MethodsLipiodol-mixed-tissue phantomy was created by intravenous alcohol（4-6 ml）into renal arteries of exvivo porcine kidneys（alcohol group）.插入具有保持器的冷冻探针（CryoHit™Needle S），该保持器在冷冻探针周围的各个位置处设置有热电偶。冷冻300 s后，评估以下内容：CT上的冰球大小、冷冻探针周围的温度分布以及0 °C和− 20 °C下的计算距离。结果CT上平均冰球直径（宽/长）：阿曲碘油组为22.1 ± 2.3/22.9 ± 2.3mm，对照组为21.6 ± 0.7/22.2 ± 1.3mm;平均冷冻探针温度为− 118 ± 3.0 °C，阿曲库碘组和− 117 ± 2.6 °C，对照组。在两组中，3 mm热电偶处的温度达到约− 50 °C，在冷冻探针约10 mm范围内< 0 °C。在与冷冻探针的平均距离为11.1 ± 0.5/6.9 ± 0.4 mm时，阿曲碘油组的温度为0/− 20 °C，在与冷冻探针的平均距离为11.0 ± 0.2/6.9 ± 0.2 mm时，对照组为0/− 20 °C。有没有显着差异，在任何变量之间groups.ConclusionThe列入组织幻影中的阿法碘油冰球的形成没有负面影响，与热导率。
PurposeTo determine whether lipiodol, which has low thermal conductivity, influences ice ball formation during cryoablation of a lipiodol-mixed-tissue phantom.Materials and MethodsLipiodol-mixed-tissue phantoms were created by injecting lipiodol (4–6 ml) into the renal arteries of ex vivo porcine kidneys (lipiodol group). A cryoprobe (CryoHit™Needle S) with a holder that was set with thermocouples at various positions around the cryoprobe was inserted. After freezing for 300 s, the followings were evaluated: ice ball size on CT, temperature distribution around the cryoprobe, and calculated distances at 0 °C and − 20 °C. Each variable was compared between lipiodol group (n= 6) those obtained in a control group without lipiodol injection (n= 6).ResultsMean ice ball diameter (width/length) on CT was 22.1 ± 2.3/22.9 ± 2.3 mm in the lipiodol group and 21.6 ± 0.7/22.2 ± 1.3 mm in the control group. Mean cryoprobe temperature was − 118 ± 3.0 °C in the lipiodol group and − 117 ± 2.6 °C in the control group. In both groups, temperature at the 3 mm thermocouple reached approximately − 50 °C and was < 0 °C within ~ 10 mm of the cryoprobe. Temperature of 0/− 20 °C occurred at a mean distance from the cryoprobe of 11.1 ± 0.5/6.9 ± 0.4 mm in the lipiodol group and 11.0 ± 0.2/6.9 ± 0.2 mm in the control group. There was no significant difference in any variable between the groups.ConclusionThe inclusion of lipiodol in a tissue phantom had no negative effects on ice ball formation that were related to thermal conductivity.