A MULTISUBUNIT COMPLEX CONTAINING THE SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, AND SNF6 GENE-PRODUCTS ISOLATED FROM YEAST
A MULTISUBUNIT COMPLEX CONTAINING THE SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, AND SNF6 GENE-PRODUCTS ISOLATED FROM YEAST
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DOI：
10.1073/pnas.91.5.1950
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发表时间：
1994-03-01
影响因子：
11.1
通讯作者：
KORNBERG, RD
中科院分区：
文献类型：
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作者：
CAIRNS, BR;KIM, YJ;KORNBERG, RD
从酿酒酵母提取物中分离纯化出一个含有SWI1/ADR6、SWI2/SNF2、SWI3、SNF5和SNF6基因产物的复合体以及4个额外的多肽。通过共沉淀和免疫共沉淀证实了这些蛋白的物理结合。一个有效的DNA依赖的ATPase与该复合体结合，这种活性与SWI2/SNF2明显相关。
A complex containing the products of the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 genes and four additional polypeptides has been purified from extracts of the yeast Saccharomyces cerevisiae. Physical association of these proteins was demonstrated by copurification and coimmunoprecipitation. A potent DNA-dependent ATPase copurified with the complex, and this activity was evidently associated with SWI2/SNF2.