Seasonal variation in symptoms of depression: A Canadian population based study
Seasonal variation in symptoms of depression: A Canadian population based study
复制标题
DOI：
10.1016/j.jad.2019.05.040
复制
发表时间：
2019-08-01
影响因子：
6.6
通讯作者：
Patten, Scott B.
中科院分区：
文献类型：
--
作者：
Lukmanji, Aysha;Williams, Jeanne V. A.;Patten, Scott B.
背景：关于抑郁症状是否随季节变化尚无共识。使用来自加拿大社区健康调查（CCHS）的数据，本研究的目的是评估加拿大家庭人口中抑郁症状的季节性变化。方法：对2015年和2016年CCHS数据进行横断面分析。采用患者健康问卷-9 （PHQ-9）平均得分和5+或10+分界点定义的分类进行分析。在回归模型中使用二次项评估季节效应，为此使用广义线性模型。模型按12-24岁的年轻人（约8000人）和25岁以上的成年人（约45000人）分层。结果：青少年（12-24岁）PHQ-9平均得分和5+分所占比例有显著的季节变化。有证据表明，随着年龄的增长，效果有所改变。与25岁以上的受访者相比，年轻人群体的季节性影响更强。PHQ-9平均分和5+分的季节效应显著（p = 0.009）， 10+分的季节效应不显著（p = 0.481）。局限性：使用横断面数据限制了将结果推广到季节性情感障碍的经典定义的能力。有关被调查者使用抗抑郁药物的数据不可用。结论：抑郁症状的季节性变化在加拿大人群中是明显的。与夏季相比，冬季报告的症状水平更高。季节性趋势在青年中最为明显，特别是那些报告至少有轻度抑郁症状的人，但在报告中度至重度症状的答复者中则不明显。
Background: There is no consensus as to whether depressive symptoms vary by season. Using data from the Canadian Community Health Survey (CCHS), the purpose of this study was to evaluate seasonal variation in depressive symptoms in the Canadian household population.Methods: A cross-sectional analysis of data from the CCHS in 2015 and 2016 was used. Mean Patient Health Questionnaire-9 (PHQ-9) scores, and categories defined by 5+ or 10+ cut-points were used for analysis. Seasonal effects were assessed using quadratic terms in regression models, generalized linear models were used for this purpose. Models were stratified by youth ages 12-24 (rounded n approximate to 8000) and adults ages 25 + (rounded n approximate to 45,000).Results: Significant seasonal variation was observed for youth (age 12-24) for mean PHQ-9 scores and proportion with scores of 5+ . There was evidence of effect modification by age. The youth group had stronger seasonal effects compared to respondents age 25+. Seasonal effect was highly significant for mean PHQ-9 scores (p = 0.009) and 5+ (p = 0.001), but not for 10+ (p = 0.481).Limitations: Use of cross-sectional data limits the capacity to generalize results to the classic definition of Seasonal Affective Disorder. Data surrounding respondent's anti-depressant use was unavailable.Conclusions: Seasonal variation in depressive symptoms is evident in the Canadian population. Higher levels of symptoms were reported in winter months compared to summer months. The seasonal trend is most pronounced in youth specifically those who reported at least mild depressive symptoms, but not in respondents reporting moderate to severe symptoms.