Levels of 12 perfluorinated chemicals in pooled Australian serum, collected 2002-2003, in relation to age, gender, and region
Levels of 12 perfluorinated chemicals in pooled Australian serum, collected 2002-2003, in relation to age, gender, and region
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DOI：
10.1021/es060301u
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发表时间：
2006-06-15
影响因子：
11.4
通讯作者：
Lindstrom, Gunilla
中科院分区：
文献类型：
--
作者：
Karrman, Anna;Mueller, Jochen F.;Lindstrom, Gunilla
从3802澳大利亚居民的合并血清样本进行了分析，四个全氟烷基磺酸盐，七个全氟烷基羧酸盐，全氟辛烷磺酰胺（PFOSA）。血清收集自五个不同年龄组的男性和女性以及澳大利亚的农村和城市地区。全氟辛烷磺酸（PFOS，20.8纳克/毫升）的平均浓度最高，其次是全氟辛酸（PFOA，7.6纳克/毫升）、全氟己烷磺酸（PFHxS，6.2纳克/毫升）、全氟壬酸（PFNA，1.1纳克/毫升）和全氟辛酸（PFOSA，0.71纳克/毫升）。在5- 18%的样品中检测到另外四种PFC，浓度接近检测限（0.1-0.5 ng/mL）。在两个区域和两种性别中，全氟辛烷磺酸浓度都随着年龄的增长而增加。与女性相比，某些年龄组的男性样本中全氟辛烷磺酸、全氟辛酸和全氟硫化氢的含量较高。相比之下，PFNA浓度较高的女性池。城市和农村地区的全氟化学品水平没有实质性差异。该水平等于或高于先前报道的欧洲和亚洲的血清水平，但低于美国。S. A.这些结果表明，北方生产排放对人类接触的重要性较小。
Pooled serum samples from 3802 Australian residents were analyzed for four perfluoroalkylsulfonates, seven perfluoroalkylcarboxylates, and perfluorooctanesulfonamide (PFOSA). Serum was collected from men and women of five different age groups and from rural and urban regions in Australia. The highest mean concentration was obtained for perfluorooctane sulfonate (PFOS, 20.8 ng/mL) followed by perfluorooctanoic acid (PFOA, 7.6 ng/mL), perfluorohexane sulfonate (PFHxS, 6.2 ng/mL), perfluorononanoic acid (PFNA, 1.1 ng/mL), and PFOSA (0.71 ng/mL). Additional four PFCs were detected in 5-18 % of the samples at concentrations near the detection limits (0.1-0.5 ng/mL). An increase in PFOS concentration with increasing age in both regions and genders was observed. The male pool levels of some of the age groups compared to females were higher for PFOS, PFOA, and PFHxS. In contrast, PFNA concentrations were higher in the female pools. No substantial difference was found in levels of PFCs between the urban and rural regions. The levels are equal or higher than previously reported serum levels in Europe and Asia but lower compared to the U. S. A. These results suggest that emissions from production in the Northern Hemisphere are of less importance for human exposure.