Estimation of effective imaging dose for kilovoltage intratreatment monitoring of the prostate position during cancer radiotherapy.

Estimation of effective imaging dose for kilovoltage intratreatment monitoring of the prostate position during cancer radiotherapy.
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DOI:
10.1088/0031-9155/58/17/5983
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发表时间:
2013-09-07
影响因子:
3.5
通讯作者:
Keall PJ
Keall PJ
中科院分区:
工程技术2区
文献类型:
--
作者:
Ng JA;Booth J;Poulsen P;Kuncic Z;Keall PJ

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Kilovoltage Intratreatment Monitoring (KIM) is a novel real-time localization modality where the tumor position is continuously measured during Intensity Modulated Radiation Therapy (IMRT) or Intensity Modulated Arc Therapy (IMAT) by a kilovoltage (kV) x-ray imager. Adding kV imaging during therapy adds radiation dose. The additional effective dose is quantified for prostate radiotherapy and compared to dose from other localization modalities. The software PCXMC 2.0 was used to calculate the effective dose delivered to a phantom as a function of imager angle and field size for a Varian On-Board Imager. The average angular effective dose was calculated for a field size of 6 cm × 6 cm. The average angular effective dose was used in calculations for different treatment scenarios. Treatment scenarios considered were treatment type and fractionation. For all treatment scenarios, (i.e. conventionally fractionated and SBRT; IMRT and IMAT), the total KIM dose at 1 Hz ranged from 2–10 mSv. This imaging dose is less than the Navotek radioactive implant dose (64 mSv) and a standard SBRT CBCT pretreatment scan dose (22 mSv) over an entire treatment regime. KIM delivers an acceptably low effective dose for daily use as a real-time image-guidance method for prostate radiotherapy.